Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients

描述(申请人提供)：本申请的目的是支持Vineet Arora，MD，MA，一位在芝加哥大学接受过奖学金培训的学术住院医师以患者为导向的研究计划和职业发展。阿罗拉博士的总体目标是发展成为一名独立的研究人员，专注于确定和改善老年住院患者的睡眠时间和睡眠质量。阿罗拉博士将在Eve Van Cauter博士的指导下发展她的研究技能，Eve Van Cauter博士是一位在正常和病理状态下的睡眠和昼夜节律方面的知名权威，重点是老年人的睡眠。David Meltzer，医学博士，一位在医院医学和卫生经济学研究方面以老龄化为重点的有成就的研究员，将担任共同导师。阿罗拉博士还将受益于格雷格·萨克斯博士、埃里克·科尔曼博士和丹尼尔·布劳纳博士等顾问团队在老年人临床护理和研究方面的集体专业知识。她还将从一个合作者团队那里获得必要的培训和研究技能，这些合作者包括：(1)Babak Mokhlesi医学博士，睡眠医学联谊会主任，他将使Arora博士能够获得睡眠医学方面的正式培训；(2)Kristen Knutson博士，他是一名研究人员和人类学家，专门使用动作图和睡眠量表来量化睡眠时间和质量；以及(3)Anirban Basu博士，统计分析专家。在拟议的奖项期间，Arora博士将通过芝加哥大学的结构化课程和课程工作获得睡眠医学、卫生服务研究和老年病学方面的正式培训。这项研究提案的总体目标是阐明环境、医疗保健和患者因素，除了患者的感知控制水平外，如何影响住院老年患者的睡眠时间和睡眠质量。此外，住院老年患者的住院睡眠(持续时间和质量)与结果(体力活动和其他健康结果)之间的关系将具有特征性。通过这段时间的职业发展和研究，阿罗拉博士将能够更好地了解住院睡眠的决定因素和影响，从而能够设计出旨在改善住院老年人医院内睡眠和相关结果的循证干预措施。 公共卫生相关性：这项研究提案的总体目标是阐明环境、医疗保健和患者因素，除了患者的感知控制水平外，如何影响住院老年患者的睡眠时间和睡眠质量。此外，住院老年患者的住院睡眠(持续时间和质量)与结果(体力活动和其他健康结果)之间的关系将具有特征性。通过这段时间的职业发展和研究，阿罗拉博士将能够更好地了解住院睡眠的决定因素和影响，从而能够设计出旨在改善住院老年人医院内睡眠和相关结果的循证干预措施。

DESCRIPTION (provided by applicant): The purpose of this application is to support the patient-oriented research program and career development of Vineet Arora, MD, MA, a fellowship-trained academic hospitalist at the University of Chicago. Dr. Arora's overall goal is to develop into an independent investigator with a focus on characterizing and improving sleep duration and sleep quality for older hospitalized patients. Dr. Arora will develop her research skills under the mentorship of Eve Van Cauter, PhD, a well-known authority on sleep and circadian rhythms in normal and pathologic states, with a focus on sleep in older persons. David Meltzer, MD, PhD, an accomplished investigator in research in hospital medicine and health economics with a focus on aging, will serve as a co- mentor. Dr. Arora will also benefit from the collective expertise in clinical care and research of older persons from a team of advisors, including Drs. Greg Sachs, Eric Coleman, and Daniel Brauner. She will also obtain necessary training and research skills from a team of collaborators including: (1) Babak Mokhlesi, MD, Director of the Sleep Medicine Fellowship, who will enable Dr. Arora to obtain formal training in sleep medicine; (2) Kristen Knutson, PhD, a research faculty and anthropologist who specializes in the use of actigraphy and sleep scales to quantify sleep duration and quality; and (3) Anirban Basu, PhD, an expert in statistical analysis. During the proposed award, Dr. Arora will obtain formal training in sleep medicine, health services research, and geriatrics through structured curricula and coursework at the University of Chicago. The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in- hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults. PUBLIC HEALTH RELEVANCE: The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in-hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults.