CORE A: Administrative and Biostatisitcs Core

摘要： 行政核心将负责管理、协调和 对整个项目进行监督。它包括科学、行政和生物统计学。 项目的专业知识，并利用参与项目的现有资源 机构。核心委员会将继续组织委员会正在举行的定期会议 并通过电子和面对面的方式促进交流。它将跟踪 每个项目和整个项目朝着商定的里程碑和 提供一个论坛，用于数据分析、发布决定和对来自 U19科学咨询小组。它将提供全面的财政监督，负责 确保遵守NIH的报告要求，并促进冲突的解决。它 还将提供通用的生物统计学来源，用于设计和分析 异种移植和艾滋病毒控制方面的实验和数据与现有的 拉贡研究所的通用数据库。它将负责前往U19的旅行 协调会议，促进学术和商业之间的互动 与会者，特别是在知识产权方面。它将明确注意到 包容和创造一种合作关注治疗艾滋病毒这一更大目标的文化 疾病。它将支持调查小组的初级成员，并提供 学员的指导关系。 核心计划的具体目标是： 目标1：创建一个具有共同目标的团队，致力于通过 开放、沟通、协作的文化 目标2：促进创业活动，以提高企业的发现能力 项目将成为现实世界的应用程序 目标3：通过跟踪单个项目的进度来管理整个项目， 确保对商定的里程碑负责，并监督交易所 信息、数据分析和出版决策 目标4：为所有项目和核心B提供生物统计学支持 目标5：确保财务和报告符合NIH标准

Abstract: The Administrative Core will be responsible for the management, coordination and supervision of the overall project. It includes scientific, administrative and biostatistical expertise for the projects and leverages existing resources at the participating institutions. The Core will organize continuation of the ongoing regular meetings of the participants and facilitate communication by electronic and in-person means. It will track progress of each project and the overall project toward agreed upon milestones and provide a forum for data analysis, publication decisions and responses to input from the U19 Scientific Advisory Panel. It will provide overall fiscal oversight, be responsible for assuring compliance with NIH reporting requirement and facilitate conflict resolution. It will also provide a common biostatistical source for the design and analysis of experiments and integrate data on xenotransplantation and HIV control with an existing common database at the Ragon Institute. It will be responsible for travel to the U19 coordinating meetings and will facilitate interactions between academic and commercial participants particularly with regards intellectual property. It will be explicitly attentive to inclusion and creating a culture of collaborative attention to the larger goal of curing HIV disease. It will be supportive of junior members of the investigative team and provide mentoring relationships for trainees. The specific aims of the Core are to: Aim 1: create a team with common purpose dedicating to curing HIV through an open, communicative and collaborative culture Aim 2: foster entreprenurial activities to enhance the ability of discoveries in the project to become real world applications Aim 3: manage the overall project by tracking the progress of individual projects, assuring accountability to agreed upon milestone and supervising the exchange of information, data analysis and publication decisions Aim 4: provide biostatistical support for all projects and Core B Aim 5: assure financial and reporting compliance with NIH standards