Macaque Resources

印度恒河猴患上一种与人类获得性免疫缺陷极为相似的疾病 当被猴免疫缺陷病毒（SIV）或嵌合猴-人感染时， 免疫缺陷病毒（SHIV），并代表了最好的动物模型的HIV感染。因为 由于猕猴和人类免疫系统的相似性，临床前疫苗的开发在很大程度上 依赖于SIV和SHIV猕猴模型。尽管它们有研究价值， 灵长类动物（NHP）是复杂的高阶物种，需要专门的基础设施和专业知识， 研究设置。NHP核心旨在巩固实验动物和细胞免疫学 艾滋病毒疫苗研究和设计（HIVRAD）项目的一部分，

The Indian rhesus macaque develops a disease that closely mimics human acquired immunodeficiency syndrome (AIDS) when infected by simian immunodeficiency virus (SIV) or chimeric simian-human immunodeficiency viruses (SHIV), and represents the best animal model for HIV infection. Because of the similarity of the immune systems of macaques and humans, preclinical vaccine development is heavily dependent on the SIV and SHIV macaque models. Their research value notwithstanding, nonhuman primates (NHPs) are complex, higher order species that require specialized infrastructure and expertise in a research setting. The NHP Core seeks to consolidate the experimental animal and cellular immunology portions of the HIV Vaccine Research and Design (HIVRAD) Program project,