Mentoring Early-Career Scientists for Drug Abuse Research Careers

描述（由申请人提供）：种族/少数民族在寻求NIH研究资金的申请人和R 01 NIH资助的研究人员中代表性不足。成瘾和多样性早期职业学习（LEAD）计划为来自代表性不足的群体或弱势背景的早期研究科学家提供培训，旨在增加在药物滥用治疗中进行行为或药理治疗研究的种族/少数民族的数量。国际环境与发展学院建立在国家药物滥用研究所临床试验网络的平台上，该网络是一个由科学家和治疗提供者组成的网络，为科学疗法的多地点测试提供了广泛的基础设施。的 培训计划还得益于与加州大学旧金山分校弗朗西斯科（UCSF）开展临床研究的培训计划和教师的密切联系，以及UCSF临床和转化科学研究所的存在。我们的具体目标是：1）将实习学者与CTN的资深科学家配对，他们将提供科学指导和专业指导，2）为学者提供支持，以进行试点研究，作为随后申请NIH的途径，3）协助学者发展赠款写作技能，目标是在LEAD培训期间提交有竞争力的NIH申请，4）提供循证治疗的文化定制培训，5）为学者提供知识和技能，以解决临床试验中遇到的伦理、监管和项目管理问题，以及6）提供网络结构，以与药物滥用临床试验研究领域的领先专家建立关系。学者将参加为期3年的培训，包括每年4-eek夏季密集计划的研讨会和会议在加州大学旧金山分校，指导和培训在学年期间，并在CTN国家研究和培训会议的参与。学者将与NIDA CTN高级调查员匹配，他们将在3年的培训期间指导他们。在第一年，学者们将设计并完成一个财政支持的试点项目 研究，参加研讨会，以帮助他们制定可资助的赠款提案，并参加CTN培训，了解当前的研究课题，并与国家领导人在药物使用研究网络。在第二年，培训的重点将是编写赠款， 来自指导项目的数据以支持培训（即，K）或研究（即，R 03、R21或R 01） 申请NIDA。在第三年，培训的重点将是重新提交国家卫生研究院的申请，如有必要，准备手稿出版，并在科学会议，包括年度CTN指导委员会会议传播研究成果。一个成功的研究或职业发展奖是参与该计划的9名早期研究人员计划的可衡量成果。该计划解决了谁拥有在美国不同的样本进行文化能力的药物滥用治疗研究的专业知识的调查人员的需求长期目标是增加从代表性不足的少数群体进行药物滥用研究的PI的数量。

DESCRIPTION (provided by applicant): Racial/ethnic minorities are underrepresented among applicants seeking NIH research funding and among R01 NIH-funded researchers. The Learning for Early Careers in Addiction and Diversity (LEAD) program provides training to early-stage research scientists from underrepresented groups or disadvantaged backgrounds, aiming to increase the number of racial/ethnic minorities who conduct behavioral or pharmacological treatment research in drug abuse treatment. LEAD builds on the platform of the National Institute on Drug Abuse Clinical Trials Network (CTN), a network of scientists and treatment providers that offers a broad infrastructure for multi-site testing of science-based therapies. The training program also benefits from strong connections to training programs and faculty conducting clinical research at University of California San Francisco (UCSF) and the presence of the UCSF Clinical and Translational Science Institute. Our specific aims are to: 1) Match trainee scholars with senior scientists in the CTN who will provide scientific mentoring and professional guidance, 2) provide scholars with support to conduct pilot research as a pathway to subsequent NIH applications, 3) assist scholars in developing grant-writing skills, with the goal of submitting competitive NIH applications during the LEAD training period, 4) offer training in cultural tailoring of evidence-based treatments, 5) provide scholars with knowledge and skills to address ethical, regulatory, and project management issues encountered in clinical trials, and 6) provide a networking structure to build relationships with leading experts in drug abuse clinical trials research. Scholars will participate in a 3-year training, consisting of a yearly 4-eek summer intensive program of seminars and meetings at UCSF, mentoring and training during the academic year, and participation in CTN national research and training meetings. Scholars will be matched with NIDA CTN senior investigators who will mentor them through the 3-year training period. In the first year, scholars will design and complete a financially supported pilot study, attend seminars to help them develop fundable grant proposals, and participate in CTN trainings to learn about current research topics and to network with national leaders in drug use research. In their second year, training will be focused on grant-writing incorporating preliminary data from the mentored project to support a training (i.e., K) or research (i.e., R03, R21, or R01) application to NIDA. In the third year, training will be focused on the re-submission of NIH applications, if necessary, preparation of manuscripts for publication, and dissemination of research findings at scientific meetings including the annual CTN Steering Committee meeting. A successful award for research or career development is the planned measurable outcome for the 9 early-stage investigators who participate in the program. The program addresses the need for investigators who have expertise in conducting culturally-competent drug abuse treatment research in diverse samples in the U.S. The long-term goal is to increase the number of PIs from underrepresented minority groups conducting drug abuse research.