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中文摘要
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赠款P51 OD 011092的5年续期要求为ONPRC的项目提供资金, 生物医学研究该申请反映了跨学科研究的战略重点,以优化 非人灵长类动物(NHP)模型的使用和开发。本申请的目的是:1)进行 最先进的研究,其中NHP是唯一适合解决人类健康问题2) 为开展跨学科生物医学研究提供区域和国家资源,特别是 因为它与NHP有关。3)追求人道和负责任的动物护理的最高标准。4)提供 为准备进入研究和生物教学职业的人提供研究培训和经验。到 为了实现这些目标,需要在八个广泛领域提供支助。 1)行政部门为ONPRC的各个方面提供所需的行政和服务支持。 各单位包括:主任办公室;行政事务处;商业事务处;设施处;信息处 系统;研究图书馆;和研究安全。2)动物服务。单位包括:资源,设施, 病理服务;组织分配计划;外科服务;行为 服务;研究、教育和培训;临床医学; NHP资源(肥胖,灵长类动物衰老, 传染病、同期交配繁殖和日本猕猴)。3)核心科学服务。单位 包括:辅助生殖技术,内分泌技术,流式细胞术,成像和形态学, 分子与细胞生物学、分子病毒学、磁共振成像和灵长类遗传学。四、 科学部分包括支持科学部门(神经科学,病理生物学和免疫学, 生殖与发育科学和糖尿病,肥胖与代谢)和跨学科 研究计划(衰老生物学,儿童早期健康与发展,灵长类遗传学研究)。 5)试点项目方案。6)改进和现代化。7)外展和社区参与。第八章) NPRC财团的活动。
英文摘要
The 5-year renewal for Grant P51OD011092 requests funding for programs at the ONPRC that support biomedical research. The application reflects a strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) Conduct state-of-the-art research for which NHPs are uniquely suited for solutions to human health problems 2) Provide a regional and national resource for the conduct of interdisciplinary biomedical research, especially as it relates to NHPs. 3) Pursue the highest standards of humane and responsible animal care. 4) Provide research training and experience for those preparing to enter research and biological teaching careers. To accomplish these aims, support is requested in eight broad areas. 1) Administration provides the administrative and service support required for all aspects of the ONPRC. Units include: the Director's Office; Administrative Services; Business Services; Facilities; Information Systems; Research Library; and Research Safety. 2) Animal Services. Units include: Resources, Facilities, and Operations; Pathology Services; the Tissue Distribution Program; Surgical Services; Behavioral Services; Research, Education and Training; Clinical Medicine; NHP Resources (Obese, Primate Aging, Infectious Disease, Time-mated Breeding, and Japanese macaque). 3) Core Science Services. Units include: Assisted Reproductive Technology, Endocrine Technology, Flow Cytometry, Imaging & Morphology, Molecular & Cellular Biology, Molecular Virology, Magnetic Resonance Imaging, and Primate Genetics. 4) Scientific Components include support for Scientific Divisions (Neuroscience, Pathobiology & Immunology, Reproductive & Developmental Sciences and Diabetes, Obesity & Metabolism) and the Interdisciplinary Research Programs (Biology of Aging, Early Childhood Health & Development, Primate Genetics Research). 5) Pilot Project Program. 6) Improvement & Modernization. 7) Outreach and Community Engagement. 8) NPRC Consortium-Based Activities.
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SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER
HIGH FAT DIET INDUCED ALTERATIONS IN GENE EXPRESSION IN THE NONHUMAN PRIMATE
SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER
SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER
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