Immunology & Pathogenesis Program Training Grant

描述（由申请人提供）：本申请的免疫学和发病机制（IMP）培训计划旨在支持10名领域领先的科学家的培训活动，他们的研究中心是免疫生物学，教师都是分子和细胞生物学系（MCB）的成员，每个人都有充足的研究支持和对指导的坚定承诺。该培训计划以MCB免疫学和病理学部门为中心，其中大多数培训教师都是成员。IMP培训计划将侧重于感染，癌症和免疫病理学背景下的基本免疫机制。我们的共同信念是，对免疫系统细胞的识别、激活、调节、分化和相互作用有一个全面的、基本的了解，这将有助于传染病、癌症和其他疾病的治疗，并且在这种方法中培训年轻的研究人员，同时提供基础分子和细胞生物学方面的广泛培训，为提高这一奋进的成功提供了最有效的途径。MCB部门和培训教师有一个长期的和明确的培训原则：早期，持续强调学生和博士后培训，为创新研究提供个人指导。该计划致力于招募和培训来自不同个人背景的学生和博士后。IMP计划将为免疫学和病理学的受训者提供一个家，并支持培训相关活动。我们建议支持3名研究生和3名博士后研究员。研究生一般将在他们的第二年开始支持，以确保对研究领域的承诺，并提供额外的信息，以评估他们提供特殊贡献的程序的能力。博士后培训生通常从第一年或第二年开始获得支持。一般来说，受训人员将获得为期两年的培训补助金支助， 由其他来源支助的额外年份。该培训补助金旨在成为NCI支持的培训补助金（分子免疫学和肿瘤生物学培训计划，T32 CA009179）的继任者，该计划支持伯克利分校的免疫学研究35年。由于研究方案的演变和该司的新招聘，该培训赠款仅限于癌症，已变得越来越具有限制性。因此，我们得出结论，NIAID支持的培训补助金更广泛地集中在免疫生物学研究上，更适合我们的团队。因此，我们正在申请这项新的培训补助金，而不是T32 CA 009179的更新。

DESCRIPTION (provided by applicant): This application for a training program in Immunology and Pathogenesis (IMP) is designed to support the training activities of ten field-leading scientists whose research centers on immunobiology, the faculty members are all members of the Department of Molecular and Cell Biology (MCB), and each has ample research support and a strong commitment to mentoring. The training program is centered in the MCB Division of Immunology and Pathogenesis, in which most training faculty are members. The IMP Training program will focus on basic immunological mechanisms in the context of infections, cancer and immunopathology. We are motivated by the shared belief that achieving a thorough, basic understanding of recognition, activation, regulation, differentiation and interactions of cells of he immune system will lead to therapies for infectious disease, cancer and other ailments, and that training young investigators in this approach, while providing broad training in basic molecular and cell biology, offers a most productive avenue for enhancing success in this endeavor. The MCB Department and the training faculty have a long-standing and defining principle for training: early, persistent emphasis on student and postdoc training for an individually directed path to innovative research. The program is strongly committed to recruiting and training students and postdocs from diverse personal backgrounds. The IMP program will provide a home for trainees in Immunology and Pathogenesis and support for training related activities. We propose support for 3 graduate students and 3 postdoctoral fellows. Graduate students will generally be supported starting in their second year to ensure commitment to the research area and to provide additional information to evaluate their capability of providing exceptional contributions to the program. Postdoctoral trainees will generally be supported starting in their first or second year. In general trainees will be supported for 2 years on the training grant, with additional years supported from other sources. The training grant is designed to be the successor of an NCI-supported training grant (Molecular Immunology and Tumor Biology Training Program, T32 CA009179), which supported immunology research at Berkeley for 35 years. Due to the evolution of the research programs and new recruitments to the Division, the focus of that training grant solely on cancer has become increasingly restrictive. We therefore concluded that an NIAID-supported training grant focused more broadly on immunobiology research is a much better fit for our group. Consequently we are applying for this new training grant rather than for a renewal of T32 CA009179.