2014 Biology of Acute Respiratory Infection Gordon Research Conference and Semina

描述(申请人提供)：本申请申请资助戈登急性呼吸道感染生物学研究会议第四次会议。这次会议将于2014年2月23日至28日在意大利的Il Ciocco举行，我们预计将有110至150名科学家参加。这次多学科会议的首要目标是提供一个展示和讨论在急性肺部感染领域的杰出研究的环境。由于感染肺部的不同病原体激活了有限数量的保守免疫反应，因此有大量信息可以由在不同病原体工作的同事和研究不同病原体的同事共享。发病机制的一般原理、先天免疫和激活局部免疫保护背后的系统生物学与许多不同类型的肺部感染高度相关。会议将持续4天半，每天早上都会发表演讲，讨论与不同类型的肺部感染相关的先天免疫的一般话题。专门讨论跨学科主题和特定病原体的会议将在上午和晚上举行，每个会议由一名经验丰富的讨论负责人领导，通常是一名在以前的会议上介绍过自己的工作的科学家。主题将包括肺部感染机制的新发展，宿主和病原体相互作用的组学方法的见解，新的先天免疫细胞和信号，桥接先天和适应性反应，联合感染及其发病机制，以及转化工作台科学以改善床边结果的进展。下午晚些时候的海报会议将提供一个非正式的场所来讨论正在进行的工作，并使研究生和博士后能够与他们感兴趣的领域的各种知名人士以及他们的同行见面。之前的戈登研究研讨会将吸引和受益于研究生和实习生。在邀请发言者和招募与会者的所有阶段，我们将努力鼓励妇女、代表人数不足的少数群体和残疾人参加。由于肺部感染是美国和全世界死亡的主要原因，这次会议与公共卫生高度相关，并可能促进疾病预防和疫苗开发的新方法。

DESCRIPTION (provided by applicant): This application requests funding to partially support the fourth meeting of the Gordon Research Conference on the Biology of Acute Respiratory Infection. This meeting will be held in Il Ciocco, Italy February 23-28 2014, and we expect 110 - 150 scientists to participate. The overarching goal of this multi-disciplinary conference is to provide a setting to present and discuss outstanding research in the area of acute lung infection. As the diverse pathogens that infect the lung activate a limited number of conserved immunologic responses, there is a great deal of information that can be shared by colleagues working in and by colleagues who study different pathogens. General principles of pathogenesis, innate immunity and the systems biology behind activation of local immune protection are highly relevant to many different types of pulmonary infection. The meeting will run for 4 1/2 days leading off with presentations each morning dealing with general topics in innate immunity relevant to diverse types of lung infection. Sessions devoted to cross-disciplinary topics and specific pathogens will be held in morning and evening sessions, each led by an experienced discussion leader, often a scientist who has presented their own work at previous meetings. Topics will include new developments in mechanisms of lung infections, insights from 'omics approaches to host and pathogen interaction, novel innate immune cells and signals, bridging innate and adaptive responses, co-infections and their pathogenesis, and advances in translating bench science to improve bedside outcomes. Late afternoon poster sessions will provide an informal venue to discuss work-in progress and enable graduate students and post-docs to meet with various luminaries in their field of interest as well as their peers. A preceding Gordon Research Seminar will attract and benefit graduate students and trainees. At all stages of speaker invitation and recruitment of attendees we will strive to encourage participation by women, underrepresented minorities and people with disabilities. As pulmonary infection is a leading cause of mortality in the USA and worldwide this conference is highly relevant to public health and will potentially foster novel approaches to disease prevention and vaccine development.