International Symposium on ALPD and Cirrhosis

描述（由申请人提供）：本R13申请旨在支持2011-2015年举行的第6 ~10届酒精性肝脏和胰腺疾病（ALPD）和肝硬化国际研讨会。这一系列专题讨论会始于2006年，非常成功地汇集了来自世界各地10~17个国家的120~200名研究人员，他们拥有尖端和互补的专业知识，并产生了大量新的合作，导致该领域的重大进展。我们希望延续这一独特和协同的传统，进一步促进ALPD和肝硬化的基础和转化研究，以及对这些影响全球数百万人的重要疾病的全球推广。研讨会的总体具体目标仍然是：1)继续促进不同学科和国家之间的国际合作；2)分享各国现有的互补性资源和专业知识，从而增加协同作用和独特的想法；3)鼓励青年研究者在国际层面进行互动；4)促进向专业和非专业社区传播有助于疾病预防和治疗的新科学和转化信息。第6 ~8届研讨会将于2011年在日本福冈、2012年在中国北京、2013年在印度德里举行，目前已确定主办单位。每个科学会议都将有一个独特的总主题和分主题。围绕“从干细胞到全球健康”的主题制定了第六届会议的初步议程，经国际咨询委员会审查，并由主办机构日本肝病学会和日本胃肠病学学会批准。专题会议包括：ALD、肝癌和胰腺癌中的干细胞；ASH与酒精性胰腺炎的细胞死亡调控肝脏和胰腺纤维化的新认识ALPD与肝硬化的新治疗方法和全球健康：酒精、吸烟和肥胖的影响。这些研讨会得到了NIAAA R13机制的部分支持，该机制为受邀的美国演讲者支付旅费，并为年轻的研究人员提供旅费奖励。主办机构不仅为会场和会议后勤提供配套支持，还为来自非美国和主办国家的受邀演讲者和年轻与会者提供配套支持。未来的专题讨论会将遵循这一分担财政责任的机制，这将确保具有成本效益的会议管理，而不会损害科学和推广的协同结果。

DESCRIPTION (provided by applicant): This R13 application seeks support for the 6th~10th International Symposium on Alcoholic Liver and Pancreatic Disease (ALPD) and Cirrhosis to be held in 2011-2015. This series of symposia began in 2006 and has been highly successful in bringing together 120~200 investigators from 10~17 nations around the world with cutting-edge and complementary expertise and generating a wealth of new collaborations that led to major advances in the field. We wish to continue this unique and synergizing tradition to further promote basic and translational research on ALPD and cirrhosis, as well as global outreach on these important diseases which affect millions of people world-wide. Overall specific aims of the symposia remain to be: 1) to continue to promote international collaboration among different disciplines and nations; 2) to share the complementary resources and expertise available in various countries, thus adding synergy and unique ideas together; 3) to encourage young investigators to interact at an international level; and 4) to promote dissemination to professional and lay communities of new scientific and translational information which can be helpful for prevention and treatment of the diseases. The 6th~8th symposia will be held in Fukuoka, Japan in 2011, in Beijing, China in 2012, and Deli, India in 2013, and their organizers have been selected. Each will have a unique general theme and subthemes for scientific sessions. A preliminary program for the 6th meeting has been created around the theme of "From Stem Cells to Global Health", reviewed by International Advisory Committee, and approved by Japanese Society of Hepatology and Japanese Society of Gastroenterology, the hosting organizations. Thematic sessions include: Stem Cells in ALD, Liver and Pancreatic Cancer; Cell Death Regulation in ASH and Alcoholic Pancreatitis; Novel Insights into Liver and Pancreatic Fibrogenesis; New Treatments of ALPD and Cirrhosis; and Global Health: Impacts of Alcohol, Smoking, and Obesity. The symposia have been supported in part by the NIAAA's R13 mechanism to defray travel costs of invited US speakers and to provide travel awards for young investigators. The hosting organization provided a matching support for the venue and meeting logistics, but also for invited speakers and young attendees from non-US and hosting nations. Future symposia will follow this mechanism of shared financial responsibility, which will assure cost-effective meeting management without compromising the synergistic outcome for science and outreach.