FASEB Science Research Conference on Skeletal Muscle Satellite and Stem Cells

描述（由申请人提供）：本申请为即将于2014年7月20日至25日在科罗拉多州蒸汽船泉举行的美国实验生物学学会联合会（FASEB）题为“骨骼肌卫星和干细胞”的会议寻求部分支持。这将是第八届卫星细胞/干细胞会议，也是第七届由FASEB主办的会议。根据过去在美国举行的FASEB会议的趋势，我们预计约有185名与会者来自世界各地（Steamboat Springs的场地容量）。本次两年一次会议的总体目标包括：1)全面分析和整合该领域的最新发现，以了解肌肉干细胞在再生、肌肉稳态、肥大、衰老和肌病状态下控制正常和异常功能的调节机制；2)创造和促进交流思想和未发表数据的互动环境，以加速发现和促进新的和现有的合作；3)为学生和初级调查员提供机会，展示他们的工作，并与高级调查员建立联系，以促进职业发展；4)通过确保在规划、执行和参与会议方案方面有适当的代表，促进妇女和其他各级代表性不足群体的职业发展。没有其他科学会议主要关注肌肉卫星和干细胞。自会议开始以来，出席会议的人数稳步增加，与会者在会后的评价也一直很好，这证明了召开这样一个会议的必要性。此外，这次会议吸引了来自世界各地的主要肌肉干细胞研究人员

DESCRIPTION (provided by applicant): This application seeks partial support for the upcoming Federation of American Societies of Experimental Biology (FASEB) conference entitled, "Skeletal Muscle Satellite and Stem Cells", which will be held July 20-25, 2014 in Steamboat Springs, Colorado. This will be the 8th conference focusing on satellite cell/stem cells and the 7th sponsored by FASEB. Based on trends from the past FASEB conferences held in the United States, we expect approximately 185 attendees from around the world (venue capacity for Steamboat Springs). The overall objectives of this biennial meeting include the following: 1) to provide a comprehensive analysis and integration of recent discoveries in the field with the goal of understanding the regulatory mechanisms controlling normal and abnormal functions of muscle stem cells in regeneration, muscle homeostasis, hypertrophy, aging and myopathic states; 2) to create and foster an interactive environment for the exchange of ideas and unpublished data to hasten discoveries and facilitate new and existing collaborations; 3) to provide opportunities for students and junior investigators to present their work and network with senior investigators to foster career development; 4) to facilitate career development of women and other underrepresented groups at all levels by ensuring appropriate representation in the planning, execution and participation in the conference program. No other scientific meeting has a primary focus on muscle satellite and stem cells. The need for a meeting with this focus is evidenced by the steady increase in attendance since the meeting's inception and the consistently excellent post-meeting evaluations by meeting attendees. In addition, this meeting attracts essentially all of the leading muscle stem cell researchers from around the world, further demonstrating the value of this meeting for established and future leaders in the field. The meeting will consist of eight platform sessions with a total of at least 44 speakers. A minimum of 16 speakers will be chosen from submitted abstracts based on the quality and impact of the work within the major themes of the conference, with inclusion of junior investigators being a priority in the selection process. The conference will also include three poster sessions, providing ample opportunity for students and junior investigators to present their work. Major themes will include transcriptional and posttranscriptional regulation of stem cells, satellite cel heterogeneity and potential, stem cell signaling and environmental interactions, satellite cell quiescence, activation and renewal, non-satellite stem cells, satellite cell proliferation, commitment and differentiation, muscle stem cells in growth and hypertrophy, and muscle stem cells in aging and disease. Collectively, this conference will provide a venue to present cutting edge research and promote collaborative interactions among all participants with the goal of advancing a fundamental understanding of muscle stem cell biology, and ultimately, translating this knowledge to the clinic.