Training in Neural Injury and Plasticity

描述（由申请人提供）：项目摘要/摘要这是一份关于神经损伤和可塑性（NIP）机构培训补助金竞争性更新的申请。我们要求支持4名高级博士生，他们将在乔治城大学神经损伤与恢复中心（CNIR）接受神经损伤和可塑性研究方面的培训。该培训计划的目的是为科学家研究创伤、中风或神经退行性过程引起的神经损伤的基本机制做好准备，并了解神经可塑性的基本机制，这可能在功能上有利于神经损伤后的修复过程。我们的目标是培养能够并致力于开发新颖有效的治疗策略以减少神经损伤导致的功能障碍的基础科学组成部分的研究人员。由27名在神经损伤和可塑性方面具有广泛研究兴趣和专业知识的经验丰富且资金充足的教师组成的团队将参加博士培训计划。学生将通过乔治城大学神经科学跨学科项目（IPN）进入研究生院。在最初的两年里，他们将参加课程学习，并在潜在导师的实验室里轮流实习。那些对NIP项目感兴趣的人将学习一门或多门特定的相关课程，开始参加NIP期刊俱乐部，并与一群杰出的临床科学家一起获得临床经验，以提供

DESCRIPTION (provided by applicant): Project Summary/Abstract This is an application for the competitive renewal of an Institutional Training Grant in Neural Injury and Plasticity (NIP). We request support for 4 advanced predoctoral students who will be trained in research on neural injury and plasticity by faculty participating in the Center for Neural Injury and Recovery (CNIR) at Georgetown University. The purpose of this training program is to prepare scientists to investigate fundamental mechanisms of neural injury, by trauma, stroke or neurodegenerative processes and to understand basic mechanisms of neural plasticity that may be functionally beneficial to the repair processes after neural injury. Our goal is to train researchers who will b capable of and committed to the basic science component of developing novel and effective treatment strategies to reduce the functional impairments that result from neural injury. An experienced and well-funded group of 27 faculty members with a wide range of research interests and expertise in neural injury and plasticity will participate in the Ph.D. training program. Students will enter graduate school through the Georgetown University Interdisciplinary Program in Neuroscience (IPN). In the first two years they will take course work and rotate through the laboratories of potential mentors. Those interested in the NIP Program will take one or more specifically relevant courses, begin to participate in the NIP Journal Club and also obtain a clinical experience with an outstanding group of clinician-scientists, to provide basic scientists with an appreciation of the experiences of patients and clinicians dealing with neural injury and plasticity. In the second year, students will formally apply to the NIP Training Program with the outline of a thesis research proposal approved by a potential mentor or co-mentors from the NIP Training Faculty. As NIP Trainees they will participate in the weekly NIP Journal Club as well as educational programs of the CNIR and plan to report results from their research in yearly student seminars, presentations at national meetings and as publications in peer reviewed journals. With respect to public health, this program will create a cadre of neuroscientists trained for research and/or management of research programs, through which new and more effective treatments for acute and degenerative disorders of the nervous system can be treated.