BIOINFORMATICS CORE

缅因州IDEA生物医学研究卓越网络（ME-INBRE）生物信息学核心将支持 通过提供必要的数据咨询和培训，开展比较功能基因组学研究 管理、生物信息学和统计分析。生物医学研究越来越多地利用高通量 技术，核心将提供专业知识，教师和学生， 管理、分析和解释大型数据集的结果。经验丰富的核心员工将提供 咨询服务，以及获得分析工具和计算基础设施，以支持 分析工作流。分析工具包括由Core员工开发的创新miRMiner工具， 已知的和新的microRNA。生物信息学核心将利用区域合作， 通过ME-INBRE共同创立的东北网络基础设施联盟（NECC） 与其他四个IDEA州合作，扩大区域网络基础设施， research.通过东北生物信息学合作（NEBC），核心将与 INBRE生物信息学特拉华州、新罕布什尔州、罗得岛和佛蒙特州的核心员工， 项目，以支持缅因州教师和合作提供生物信息学培训的教师和学生。 区域网络基础设施将用于密集计算和集中数据存储， 和后援一系列的生物信息学研讨会将在缅因州和地区范围内举行 通过NEBC为ME-INBRE研究者、研究培训学院提供研究培训， 学生，沿着与其他缅因州教师和学生。核心还将举办新的生物信息学 学者计划为MEINBRE的学生提供单独指导的生物信息学研究项目 机构职能体系总而言之，核心小组将提供以下方面的知识和技术专长及培训： ME-INBRE研究人员和研究培训学院需要完成的生物信息学 研究目标。

The Maine IDeA Network for Biomedical Research Excellence (ME-INBRE) Bioinformatics Core will support research in comparative functional genomics by providing essential consulting and training in data management, bioinformatic and statistical analysis. Biomedical research increasingly utilizes highthroughput technologies, and the Core will provide specialized expertise to faculty and their students for managing, analyzing and interpreting results from large data sets. Highly experienced Core staff will provide consultation services, as well as access to analysis tools and computational infrastructure, to support analysis workflows. Analysis tools include the innovative miRMiner tool developed by Core staff to analyze known and novel microRNAs. The Bioinformatics Core will leverage regional collaborations and cyberinfrastructure through the Northeast Cybennfrastructure Consortium (NECC) that ME-INBRE cofounded with four other IDeA states to expand regional cyberinfrastructure and conduct collaborative cyberenabled research. Through the Northeast Bioinformatics Collaborative (NEBC), the Core will work with INBRE Bioinformatics Core staff in Delaware, New Hampshire, Rhode Island, and Vermont on consulting projects to support Maine faculty and collaborate on delivering bioinformatics training to faculty and students. Regional cyberinfrastructure will be used for intensive computations and centralized data storage, sharing and backup. A series of bioinformatics workshops will be given both within Maine and also regionally through the NEBC to provide research training to ME-INBRE Investigators, Research Training Faculty, and students, along with other Maine faculty and students. The Core will also host the new Bioinformatics Scholars Program to provide individually mentored bioinformatics research projects for students at MEINBRE institutions. In summary, the Core will provide the intellectual and technical expertise and training in bioinformatics that ME-INBRE Investigators and Research Training Faculty need to accomplish their research goals.