2022 Cell Biology of the Neuron Gordon Research Conference and Gordon ReSeminar

摘要 我们正在申请资金支持2020年戈登神经元细胞生物学研究会议， 以及为初级科学家和实习生举办的相关戈登研究研讨会。会议将举行 华盛顿州沃特维尔山谷，2020年6月28日至7月3日，紧随其前的GRS(6月27日至28日)。这个 这次会议的主要焦点是细胞生物学和神经科学之间的接口。驱动力 因为这个主题是认识到要理解复杂的神经元交流，我们需要 了解发生在神经元中的复杂细胞生物学。对分子和细胞的理解 神经功能还将有助于解决与神经发育和神经退行性变有关的问题 精神错乱。神经元会议的细胞生物学一直是，并将继续是一个突出的 就有助于推动发展的最新发现进行批判性的出版前讨论的平台 我们对神经细胞生物学的理解。2020年的会议将突出这方面的新兴主题 跨学科领域，重点是运输机械和轴突的结构组织 突触，控制神经元形状、大小和功能的机制，翻译和蛋白质 健康和疾病中的动态平衡，神经元-神经胶质细胞的相互作用和交流以及新的 技术转型。会议计划将通过将这些主题汇集在一起来研究这些主题 演讲者来自不同的领域、背景和职业阶段。大力强调促进 与会者之间激烈的研究讨论和新的合作。特邀演讲者包括两位 杰出的资深科学家和后起之秀，相当大比例的演讲将从 初级科学家提交的摘要。我们预计，这一组合将产生一种刺激 交流思想，并将在未来带来令人振奋的新研究方向。我们的建议有两个 具体目标：通过汇聚一位 一群杰出的科学家在一个项目中强调神经元形状、结构的新兴主题 和规模在健康和疾病中发挥作用；并激励初级科学家和受训人员，促进科学 互动，增加了跨学科领域的思想、背景和培训的多样性 神经细胞生物学。多学科主题和共同关注将促进跨领域的沟通 分子和细胞神经生物学的整个连续体。同样重要的是，我们寻求一种 互动和包容的环境，其特点是受邀发言者之间进行活跃的讨论， 讨论领袖、海报演示者和所有会议参与者。这些目标加在一起将导致 为了更好地了解神经元的独特生物学特性，并改进策略 解决未来毁灭性的神经性疾病。

Summary We are requesting funds to support 2020 Gordon Research Conference on the Cell Biology of the Neuron, and the associated Gordon Research Seminar for junior scientists and trainees. The meeting will be held Waterville Valley, NH, June 28- July 3, 2020, with the GRS immediately preceding (June 27-28). The main focus of this conference is the interface between cell biology and neuroscience. The driving force for this theme is the realization that to understand the complex neuronal communication, we need to understand the complex cell biology occurring in neurons. A molecular and cellular understanding to neuronal function will also help tackle questions related to neurodevelopmental and neurodegenerative disorders. The Cell Biology of the Neuron meeting has always been, and continues to be a prominent platform for critical, pre-publication discussion on the recent discoveries that contribute to move forward our understanding of neuronal cell biology. The 2020 conference will highlights emerging topics in this interdisciplinary field, with a focus on transport machinery and structural organization in axons and synapses, mechanisms controlling neuron al shape, size and function, translation and protein homeostasis in health and disease, neuron-glia interaction and communication as well as new transforming technologies. The meeting program will examine these themes by bringing together speakers form diverse fields, background and career stages. A strong emphasis is placed on promoting intense research discussions and new collaborations among attendees. Invited speakers include both outstanding senior scientists and rising stars, with a significant proportion of talks to be selected from abstracts submitted by junior scientists. We anticipate that this combination will result in a stimulating exchange of ideas and will lead to exciting new research directions in future. Our proposal has two specific aims: to stimulate progress in the field of neuronal cell biology, by bringing together an exceptional group of scientists in a program emphasizing emerging themes in neuronal shape, structure and size to function in health and disease; and to inspire junior scientists and trainees, facilitating scientific interactions, increasing the diversity of ideas, background, and training in the interdisciplinary field of neuronal cell biology. The multidisciplinary theme and shared focus will facilitate communication across the entire continuum of molecular and cellular neuronal biology. Just as importantly, we seek an interactive and inclusive environment characterized by lively discussions between invited speakers, discussion leaders, poster presenters, and all meeting participants. Together, these objectives will lead to a better understanding of the unique biology characteristic of neurons, and to improved strategies for addressing devastating neuronal diseases in future.