Learning the mechanisms of programmed cell death and tumour suppression to develop novel cancer therapies

我们的身体通过肿瘤抑制过程防止癌症的发展，这也影响癌症治疗的结果。程序性细胞死亡（细胞凋亡）就是这样一个过程，细胞凋亡的缺陷促进癌症发展并损害肿瘤细胞对抗癌疗法的反应。我的实验室使用分子生物学和细胞生物学方法来研究细胞死亡和肿瘤抑制的机制，与制药公司合作开发新的癌症疗法。

Our bodies prevent the development of cancer through tumour suppressive processes, which also affect the outcome of cancer therapy. Programmed cell death (apoptosis) is one such process, and defects in apoptosis promote cancer development and impair the response of tumour cells to anti-cancer therapies. My laboratory uses molecular biology and cell biology approaches to investigate the mechanisms of cell death and tumour suppression, partnering with pharma to develop novel cancer therapies.