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中文摘要
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描述(由申请人提供):费城儿童医院(CHOP)建议继续我们由NICHD赞助的儿童健康研究职业发展奖(CHRCDA)K12培训计划。我们的目标是通过识别和培训有前途的儿科教员成为成功的内科科学家,并通过鼓励这些人解决对儿童健康和疾病至关重要的问题,来增加在分子技术方面经过严格培训和良好技能的儿科专科医生的数量和效率。我们计划的候选人将是CHAP初级教员,他们要么是从我们优秀的次级专业奖学金受训人员库中任命的,后者又是通过全国搜索来确定最优秀和最聪明的人,或者是从通过广泛招聘战略确定的候选人中挑选出来的。我们将每年资助3名儿科专科奖学金项目的毕业生,并为每位学者提供平均两年的资助。每名候选人将从44名导师中选择一名未来的导师,其中39名来自CHOP(儿科学、病理学和外科),5名来自宾夕法尼亚大学(Penn)。这些CHRCDA导师是根据以下标准选择的:与儿科相关的领域的严谨科学和生产力,通过协作研究互动成功指导的良好记录,外部资金的良好记录,以及计划平衡。儿科学者将进行他们的正式研究申请中概述的研究。他们将随时进入一系列全面的研究核心实验室,并将有充足的机会在正式和非正式的环境中与高级和其他初级调查人员交流意见。在过去的20年里,我们在催生能够进行基础独立研究的内科科学家方面取得了极大的成功。我们已经培训了54名来自不同次级专业的儿科学者,这些学者在出版、赠款支持、学术职位和领导职位方面都取得了极大的成功。我们的多元化招聘官员领导一项计划,招募、保留、指导和激励来自代表性不足的少数族裔、残疾人或其他弱势群体的内科科学家,他们将在儿科医学研究中担任重要角色。除了首席调查员/项目主任、培训主任和多元化招聘官员外,我们还有内部顾问和外部咨询委员会,负责以下职责:1)征集和挑选申请者;2)监督CHRCDA儿科学者计划的进展;3)评估CHRCDA作为职业发展计划的整体有效性。这笔赠款利用了CHOP作为一家学术儿科机构的巨大优势,拥有一批杰出的子专业研究员、大量经验丰富的导师和尖端研究项目。CHOP和宾夕法尼亚大学提供了一个非常全面、得到良好支持和资源密集的环境,以及在培训基础和翻译学术研究人员成为独立的内科科学家方面的可靠记录。
英文摘要
DESCRIPTION (provided by applicant): The Children's Hospital of Philadelphia (CHOP) proposes to continue our NICHD-sponsored Child Health Research Career Development Award (CHRCDA) K12 Training Program. Our goal is to increase the number and effectiveness of subspecialty pediatricians with rigorous training and well developed skills in molecular techniques by identifying and training promising pediatric faculty to become successful physician-scientists, and by encouraging these individuals to address questions of fundamental importance to health and disease in children. Candidates for our program will be CHOP junior faculty either appointed from our outstanding pool of subspecialty fellowship trainees, who in turn are identified through national searches to identify the best and the brightest, or from candidates identified by broad recruitment strategies. We will support 3 Scholars per year who are graduates of Pediatric Subspecialty Fellowship Programs, and support each Scholar for an average of two years. Each candidate will choose a prospective mentor from a group of 44 mentors, 39 from CHOP (Pediatrics, Pathology, and Surgery) and five from the University of Pennsylvania (Penn). These CHRCDA mentors were chosen by the following criteria: rigorous science and productivity in areas germane to pediatrics, a strong record of successful mentoring with collaborative research interactions, a strong record of extramural funding, and programmatic balance. Pediatric Scholars will conduct research as outlined in their formal research applications. They will have ready access to a comprehensive array of research core laboratories, and they will have ample opportunity to exchange ideas in both formal and informal settings with senior and other junior investigators. In the past 20 years, we have been highly successful in catalyzing the production of physician-scientists capable of conducting fundamental, independent research. We have trained 54 Pediatric Scholars from a wide range of subspecialties, and these Scholars have been highly successful in terms of publications, grant support, academic positions, and positions of leadership. Our Diversity Recruitment Officer leads a plan to recruit, retain, mentor, and inspire physician-scientists from underrepresented minorities, persons with disabilities, or other disadvantaged persons who will assume prominent roles in pediatric medical research. Besides the Principal Investigator/Program Director, Training Director and Diversity Recruitment Officer, we have Internal Advisors and an External Advisory Committee that have the following responsibilities: 1) solicit and select applicants; 2) monitor the progress of CHRCDA Pediatric Scholars; and 3) assess the overall effectiveness of the CHRCDA as a career development program. This grant takes advantage of the tremendous strengths of CHOP as an academic pediatric institution with an outstanding pool of subspecialty fellows, a large number of experienced mentors, and cutting edge research programs. CHOP and Penn provide a very comprehensive, well-supported and resource-intense environment, as well as a proven track record of training basic and translational academic investigators to become independent physician-scientists.
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Pathogenicity of the emerging pathogen Kingella kingae
  • 批准号:
    10559927
  • 项目类别:
  • 资助金额:
    $44.5万
  • 财政年份:
    2022
  • 负责人:
    Joseph W. St. Geme
  • 依托单位:
Molecular basis of virulence in the emerging pathogen Kingella kingae
  • 批准号:
    8731463
  • 项目类别:
  • 资助金额:
    $39.36万
  • 财政年份:
    2013
  • 负责人:
    Joseph W. St. Geme
  • 依托单位:
Biology of the HMW1 and HMW2 Adhesins of H. Influenzae
  • 批准号:
    7850275
  • 项目类别:
  • 资助金额:
    $14.49万
  • 财政年份:
    2009
  • 负责人:
    Joseph W. St. Geme
  • 依托单位:
Center for Molecular & Cellular Studies of Ped Disease
  • 批准号:
    7001196
  • 项目类别:
  • 资助金额:
    $43.2万
  • 财政年份:
    2003
  • 负责人:
    Joseph W. St. Geme
  • 依托单位:
海外基金