Pilot Project Core

路易斯维尔大学酒精研究中心（ULARC）的成立是为了作为一个 区域/国家资源，以调查酒精引起的器官损伤的机制， 预防/治疗这种器官损伤的新药物/干预措施，这两者都是重要的未满足的 研究需要。该中心的主题是独一无二的酒精中心：营养的作用， 酒精诱导的器官损伤的发生/进展和潜在的预防/治疗。的 Pilots Core将通过资助致力于这一研究主题的新项目来为该计划做出贡献。我们将 通过支持年轻的调查员，以及招募成熟的调查员，他们建议 这些项目代表了他们研究方向的变化。试点核心的目标是提供支持， 酒精性器官损伤的临床和转化研究。这种支持将有针对性地 主要是新的研究者，那些新进入酒精临床和转化研究， 跨部门和机构合作的临床/翻译研究者。我们将提供一个 环境，通过向酒精研究人员提供 进行创新性临床/转化研究所需的信息、资源和指导， 21世纪世纪科学的要求。此外，我们还将改善有关现有和 新的机会和资源的大学组成部分和我们的附属机构之间的试点项目。的 ULARC将为寻求进行酒精研究的研究人员提供一个明确的切入点。我们将到达我们的 （1）请求与联合国协调的潜在试点项目， ULARC的总体主题：营养和酒精引起的器官损伤; 2）协调评估 符合ULARC试点计划标准和目标的新试点项目申请; 3)协助试点项目的接受者获得校外资助。该试点计划将建立在UofL的 在确定有希望获得支助的试点项目方面已经取得了出色的成绩。建立了ULARC， 该试验计划将大大增加目前可用的试验计划资金， 刺激UofL的新型酒精研究。

The University of Louisville Alcohol Research Center (ULARC) was created to serve as a regional/national resource to investigate mechanisms of alcohol induced organ injury and to develop new agents/interventions to prevent/treat this organ injury, both of which represent important unmet research needs. The theme of the center is unique among alcohol centers: the role of nutrition in the development/progression and potential prevention/treatment of alcohol-induced organ injury. The Pilots Core will contribute to this program by funding new projects dedicated to this theme of research. We will do this by supporting Young Investigators, as well as recruiting Established Investigators, who propose projects that represent a change in direction for their research. The goal of the Pilot Core is to provide support for promising clinical and translational research in alcohol-induced organ injury. This support will be targeted mainly at new investigators, those newly entering alcohol clinical and translational research, and alcohol clinical/translational investigators collaborating across departments and institutions. We will provide an environment that encourages development of pilot projects by providing alcohol researchers with the information, resources and mentoring needed to perform innovative clinical/translational research that meets the demands of 21st century science. In addition, we will improve the flow of information about existing and new opportunities and resources for pilot projects among University components and our affiliates. The ULARC will provide a clear entry point for investigators seeking to conduct alcohol research. We will reach our goal through the following Specific Aims: 1) To request potential pilot projects that coordinate with the overall theme of the ULARC: Nutrition and Alcohol-Induced Organ Injury; 2) To coordinate evaluation of new pilot project applications which conform to the criteria and goals of the ULARC pilot program; 3) To assist pilot project recipients to achieve extramural funding. This Pilot Program will build on UofL's already outstanding record of identifying promising pilot projects for support. Establishment of the ULARC and the Pilot Program will provide a significant boost to the currently available pilot program funding and greatly stimulate novel alcohol research at UofL.