Research Fellowship in Geriatric Mood Disorders

 描述(由申请人提供)：这是T32老年情绪障碍研究奖学金项目的第六个竞争性申请，该项目提供多学科培训已有25年之久。随着科学发展、国际移民组织的要求、2015年NIMH战略优先事项、RDoC项目以及我们现有教员不断发展的专业知识，这一成功的T32经历了持续的转变。新的T32以连续的方式组织其研究培训，其中我们的临床神经生物学研究为我们的新治疗开发计划提供目标，我们的服务研究旨在扩大社区精神健康治疗的质量和覆盖范围。该计划的优势是：1)受训人员的学术记录；过去10年培训的13名研究员获得了17项奖学金，并共同撰写了94篇论文(44篇为第一作者)；2)在国家一级的研究培训方面的领导地位(NIMH夏季研究所和NIMH高级研究所的PI)；3)由NIMH资助的翻译研究教员，范围包括分子遗传学、神经成像、临床药理学、干预开发和心理健康服务研究；4)团结一致地组织韦尔康奈尔老年精神病学研究所；5)四个康奈尔试点项目；6)丰富的研究人群和实验室资源；7)可供研究员进行二次分析和生成假设的数据库；8)与老年医学、普通内科、临床流行病学和服务研究计划、公共卫生和医学伦理学的研究人员进行长期和有效的合作；以及9)在9个多站点研究中发挥领导作用。该计划将由临床神经生物学(F.Gunning)、新型治疗开发(G.Alexopoulos)和服务研究(M.Bruce)等领域的资助研究人员指导，他们在研究培训方面有良好的记录，并由一个在分子遗传学、神经成像、治疗开发、伦理学和少数族裔研究方面拥有专业知识的执行委员会指导。我们请求为3个实习生提供支持，他们的个性化培训计划将由两名导师(例如一名临床和一名基础研究人员)协调，以促进翻译研究。除了核心课程外，我们还支持学员进行自己的学习，准备竞争性资助申请，以及 发表基于数据的论文。

 DESCRIPTION (provided by applicant): This is the sixth competing application of the T32 Research Fellowship Program in Geriatric Mood Disorders, which has been offering multidisciplinary training for 25 years. This successful T32 has undergone continuous transformation in response to scientific developments, IOM mandates, the 2015 NIMH Strategic Priorities, the RDoC Project, and the evolving expertise of our current faculty. The new T32 organizes its research training in a continuum in which our clinical neurobiology studies provide targets for our novel treatment development initiatives and our services research seeks to extend the quality and reach of mental health treatment in the community. The Program's strengths are: 1) The academic record of its trainees; the 13 fellows trained of the past 10 years received 17 grants and coauthored 94 papers (44 first-authored); 2) Leadership in research training at a national level (PIs of the NIMH Summer Research Institute and the NIMH Advanced Research Institute); 3) NIMH-funded faculty in translational research ranging from molecular genetics, neuroimaging, clinical pharmacology, intervention development, and mental health services research; 4) Cohesive organization of the Weill Cornell Institute of Geriatric Psychiatry; 5) Four Cornell pilot project programs; 6) Rich study populations and laboratory resources; 7) Databases available for secondary analyses and hypothesis generation by fellows; 8) Long and effective collaboration with investigators of Geriatric Medicine, General Internal Medicine, Clinical Epidemiology and Services Research Program, Public Health and Medical Ethics; and 9) Leadership in 9 multisite studies. The Program will be directed by funded investigators in clinical neurobiology (F. Gunning), novel treatment development (G. Alexopoulos) and services research (M. Bruce) with a strong record in research training and by an Executive Committee with expertise in molecular genetics, neuroimaging, treatment development, ethics, and minority studies. We request support for 3 trainee slots, whose personalized training programs will be coordinated by two mentors (e.g. one clinical and one basic investigator) to facilitate translation research. Beyond a Core Curriculum, we support our trainees in conducting their own studies, in preparing applications for competitive funding, and in publishing data-based papers.