Scientific Information Management and Literature-Based Evaluations for the National Toxicology Program (NTP) – Support for the DNTP Office of Nomination and Selection

一个涉及镇痛剂对发育/生殖影响的项目正在进行中，以支持国家麻醉品管理局提名和甄选办公室;国家麻醉品管理局正在制定其他项目。国家统计局负责监督化学品、其他候选物质以及NTP研究或审查的问题的正式提名、审查和选择过程。为了支持这一进程，国家统计局管理背景审查和概念文件的研究或审查提名的发展，以促进项目开发，公众沟通，演示和科学顾问的NTP委员会审查。这些项目需要承包者提供科学和技术专门知识和支持，以汇编、审查和分析来自科学文献和其他来源的关于环境物质的影响和可能影响公众健康的其他问题的信息和数据。 关键词：系统综述、毒理学、流行病学、暴露、癌症、非癌症效应

A project involving developmental/reproductive effects of analgesics to support the DNTP Office of Nomination and Selection (ONS) is in progress; additional projects are under development by DNTP. The ONS oversees a formal nomination, review, and selection process for chemicals, other candidate substances, and issues to be studied or reviewed by the NTP. To support this process, the ONS manages the development of background review and concept documents on nominations for research or review to facilitate project development, public communication, presentation, and review by the NTP Board of Scientific Counselors. These projects involve scientific and technical expertise and support from the contractor to compile, review, and analyze information and data from the scientific literature and other sources regarding the effects of environmental substances and other issues that may impact public health. Keywords: Systematic review, toxicology, epidemiology, exposure, cancer, non-cancer effects