Research Tranining in Cellular and Molecular Biology

 描述(由申请人提供)：本提案寻求更新加州大学洛杉矶分校的博士前细胞和分子生物学(CMB)培训计划。CMB计划旨在继续培训下一代年轻男女，他们将引领分子和细胞生物学方法的创新，以改善人类健康。该计划侧重于基础广泛的培训，强调学员之间的互动和跨学科研究，为准备充分利用基因组学、蛋白质组学和代谢组学以及成像、质谱学和大分子结构分析等领域的技术进步的科学家做好准备。该方案非常重视研究、诚信培训以及加强多样性和扩大未得到充分代表的科学家队伍。目前的培训教师来自加州大学洛杉矶分校文理学院和邻近的加州大学洛杉矶分校医学院，包括化学和生物化学、分子、细胞和发育生物学、微生物学、免疫学和分子遗传学、生物化学、医学、整形外科、病理和实验室医学等系的32名成员。主要研究领域包括生物化学、细胞生物学、发育生物学、基因表达、大分子结构、分子和细胞免疫学、神经生物学、干细胞生物学、病毒学和微生物病理学。学员从分子生物学系间博士项目(基因调控；细胞和发育生物学；生物化学、生物物理学和结构生物学；免疫、微生物和分子病理学)以及生物化学、分子和结构生物学博士项目的四个国内领域中挑选出来。学生是根据他们的学术和研究成就，以及他们在互动和跨学科环境中蓬勃发展的承诺，在我们的咨询委员会审查后被任命的。除了与大学会面外 ，学员参加专门为CMB项目开发的课程，包括中级和高级研究完整性课程(化学250和203D)，以及研讨会课程(化学204)，让学生向他们的同事和培训教师谈论他们的研究 他们的论文工作阶段和准备个人发展计划(IDP)。为鼓励代表性不足的学生从事细胞和分子生物学职业而开展的外展、招聘和指导活动也是该计划的重要组成部分。该培训计划为期三年，需要34名博士前实习生，以满足对非常高素质学生的强烈需求。这些设施是一个主要的本科生和研究生校园的设施，大约有3.5万名学生，其中包括一名医学院教职员工。参与该项目的所有实验室都很接近，这有利于学生和教职员工之间的互动。这一连贯和互动的项目大大加强了加州大学洛杉矶分校细胞和分子生物学方面的博士研究。

 DESCRIPTION (provided by applicant): This proposal seeks renewal for UCLA's predoctoral Cellular and Molecular Biology (CMB) Training Program. The CMB program aims to continue to train the next generations of young men and women that will lead innovation in molecular and cellular biology approaches to improving human health. The program focuses on a broad based training that emphasizes trainee interactions and interdisciplinary studies to prepare scientists who will be poised to take full advantage of technological advances in genomics, proteomics, and metabolomics, as well as in fields such as imaging, mass spectrometry, and macromolecular structure analysis. The program has a strong emphasis on research integrity training and on enhancing diversity and enlarging the pool of underrepresented scientists. The current training faculty comes from both the UCLA College of Letters and Sciences and the adjacent UCLA School of Medicine, including 32 members of the Departments of Chemistry and Biochemistry; Molecular, Cell and Developmental Biology; Microbiology, Immunology and Molecular Genetics; Biological Chemistry; Medicine; Orthopedic Surgery, and Pathology and Laboratory Medicine. Major research areas include biochemistry, cell biology, developmental biology, gene expression, macromolecular structure, molecular and cellular immunology, neurobiology, stem cell biology, virology and microbial pathology. Trainees are selected from the four home areas of the Molecular Biology Interdepartmental PhD program (Gene Regulation; Cell & Developmental Biology; Biochemistry, Biophysics, and Structural Biology; Immunity, Microbes & Molecular Pathogenesis) as well as the PhD program in Biochemistry, Molecular, and Structural Biology. Students are appointed after review of our Advisory Committee based on their academic and research achievements, as well as their promises to flourish in an interactive and interdisciplinary environment. In addition to meeting the university and departmental or program requirements for their degrees, trainees participate in courses developed specifically for the CMB program including intermediate and advanced research integrity classes (Chem 250 and 203D), as well as seminar classes (Chem 204) that let students talk about their research to their fellow trainees and to the training faculty at multiple stages of their thesis work and prepare individual development plans (IDPs). Outreach, recruitment, and mentoring activities for encouraging underrepresented students to have careers in cellular and molecular biology is also an important part of the program. The training program is for three years and 34 predoctoral trainees are requested to meet the strong demand for this training of very highly qualified students. The facilities are those of a major undergraduate and graduate campus of approximately 35,000 students that includes a medical school faculty. All of the laboratories involved in this program are in close proximity to each other, which facilitates interactions of both students and faculty. This coherent and interactive program has significantly strengthened PhD studies in cellular and molecular biology at UCLA.