2011 Molecular and Cellular Biology of Lipids Gordon Research Conference

2011年脂质分子和细胞生物学戈登研究会议

• 批准号: 8129101
• 负责人: Judith Storch
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129101
• 关键词: Address; Area; Basic Science; Binding; Biological; Cardiovascular Diseases; Cardiovascular system; Cell membrane; Cells; Cholesterol; Chronic Disease; Clinical Medicine; Communicable Diseases; Communities; Complex; Coupled; Development; Diabetes Mellitus; Disabled Persons; Disease; Equilibrium; Ethnic Origin; Evaluation; Fatty acid glycerol esters; Fostering; Future; Gene Expression; Genetic; Health; Human; Individual; Inflammatory; Interdisciplinary Study; International; Life; Lipid Biochemistry; Lipids; Maintenance; Malignant Neoplasms; Metabolic Diseases; Metabolic syndrome; Metabolism; Methodology; Molecular; Molecular Biology; Molecular and Cellular Biology; Myocardial Infarction; New Hampshire; Obesity; Participant; Phospholipid Metabolism; Play; Process; Proteins; Recording of previous events; Regulation; Research; Research Personnel; Resort; Role; Science; Scientist; Signal Transduction; Signaling Molecule; Sterols; Stroke; Structural Biologist; Woman; Yeasts; Youth; biological systems; cancer type; design; experience; frontier; graduate student; handicapping condition; lectures; lipid metabolism; lipid transport; meetings; membrane model; men; metabolic abnormality assessment; novel; novel therapeutics; planetary Atmosphere; posters; programs; success; symposium; therapeutic development

DESCRIPTION (provided by applicant): This application is for partial support of the 2011 Gordon Research Conference (GRC) on Molecular and Cellular Biology of Lipids, a meeting that will bring together leading scientists in the field to present and discuss their research and to facilitate advances in lipid research. This conference has been held every other year for almost 50 years and is nationally and internationally recognized as a prestigious forum for the presentation of ground breaking research in lipid biochemistry and molecular biology. In 2011, the conference will focus heavily on the continuing emergence of lipids in understanding the mechanisms of health maintenance and chronic disease development. The meeting will be held July 17 - 22 at the Waterville Valley Resort in Waterville Valley, New Hampshire, and will include nine lecture sessions and four afternoon poster sessions. Lecture sessions will cover a broad range of topics, including the genetic regulation of lipid metabolism, cellular lipid trafficking, regulation of sterol metabolism, function and regulation of phospholipid metabolism, intracellular storage of neutral lipids, lipids and cell signaling, novel methodologies and lipid frontiers, and the molecular mechanisms of metabolic diseases. The >32 speakers in these sessions will describe research done in an array of biological systems, from humans to yeast to model membranes, and using multiple experimental approaches. The talks at the Molecular and Cellular Biology of Lipids GRC, as well as the large and lively poster sessions, are well known to stimulate dynamic discussions among attendees who in this case will include biochemists, cell biologists, geneticists, molecular biologists, structural biologists, and physiologists. Scientists who attend this conference derive synergistic benefit from close interactions with the high quality speakers and the diverse experimental backgrounds of both the speakers and the participants, all fostered by the intimate atmosphere of the meeting, which is limited to about 150 participants. These benefits in turn drive future advances and multidisciplinary collaborations in the field. Participants and speakers have been and will be chosen to reflect international excellence in this medically-relevant area of science, with an ideal balance between youth and experience. The program includes outstanding women and men, and scientists of many different ethnicities. Superb facilities are available to accommodate handicapped individuals. PUBLIC HEALTH RELEVANCE: Lipids such as fats and cholesterol are required for life, but cause heart attacks and strokes when present in excess. It is also now known that lipids play an important role in the development of other metabolic syndrome disorders including diabetes, obesity, and some types of cancer. The 2011 Gordon Research Conference on the Molecular and Cellular Biology of Lipids will address current issues in lipid metabolism, and how the fundamental processes of lipid synthesis, breakdown, and storage go awry in cardiovascular and other diseases.

描述(由申请人提供)：此申请是为了部分支持2011年戈登研究会议(GRC)关于脂质的分子和细胞生物学，该会议将聚集该领域的领先科学家介绍和讨论他们的研究，并促进脂质研究的进展。近50年来，该会议每隔一年举行一次，是国内和国际公认的展示脂质生物化学和分子生物学开创性研究的著名论坛。2011年，会议将重点关注血脂的持续出现，以了解健康维持和慢性病发展的机制。会议将于7月17日至22日在新罕布夏州沃特维尔山谷的沃特维尔山谷度假村举行，将包括9场讲座和4场下午的海报会议。讲座将涵盖广泛的主题，包括脂类代谢的遗传调控，细胞脂类的运输，类固醇代谢的调控，磷脂代谢的功能和调控，中性脂类、脂类和细胞信号的细胞内储存，新的方法和脂类的前沿，以及代谢性疾病的分子机制。在这些会议上，32位演讲者将介绍在一系列生物系统中进行的研究，从人类到酵母再到膜模型，并使用多种实验方法。众所周知，在脂质的分子和细胞生物学GRC上的演讲，以及大型而生动的海报会议，都会激发与会者之间的动态讨论，在这种情况下，与会者将包括生物化学家、细胞生物学家、遗传学家、分子生物学家、结构生物学家和生理学家。参加这次会议的科学家从与高质量演讲者的密切互动以及演讲者和参与者的不同实验背景中获得协同效益，所有这些都是由会议的亲密氛围培育的，会议限制在150人左右。这些好处反过来又推动了该领域未来的进步和多学科合作。与会者和演讲者已经并将被挑选出来，以反映这一与医学相关的科学领域的国际卓越表现，并在青年和经验之间取得理想的平衡。该项目包括杰出的女性和男性，以及许多不同种族的科学家。提供一流的设施来容纳残障人士。 与公共健康相关：脂肪和胆固醇等脂类是生命所必需的，但过量时会导致心脏病发作和中风。现在也知道，血脂在糖尿病、肥胖症和某些类型的癌症等其他代谢综合征疾病的发展中起着重要作用。2011年戈登脂质分子和细胞生物学研究会议将探讨目前脂代谢方面的问题，以及在心血管和其他疾病中脂质合成、分解和储存的基本过程是如何出错的。