New Cardiovascular Research Scientist for Molecular and Cellular Biology Core

分子和细胞生物学核心的新心血管研究科学家

• 批准号: 7860808
• 负责人: James T. Willerson
• 金额: $ 54.17万
• 依托单位: TEXAS HEART INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7860808
• 关键词: Cardiac; Cardiac Myocytes; Cardiovascular Diseases; Cardiovascular system; Chromatin Remodeling Factor; Commit; Congenital Abnormality; Congenital Heart Defects; Data; Development; Diagnostic; Funding; Gene Expression; Gene Expression Profile; Genes; Genetic; Genetic Transcription; Heart; Human; Innovative Therapy; Institutes; Knowledge; Malignant Neoplasms; Modification; Molecular; Molecular Genetics; Molecular and Cellular Biology; Mus; Pathway interactions; Peptide Hydrolases; Post-Translational Protein Processing; Regulation; Research; Research Personnel; Resources; Role; Scientist; Site; Texas; Therapeutic; Transgenic Mice; base; cardiogenesis; career; chromatin remodeling; congenital heart disorder; experience; insight; mouse model; multidisciplinary; mutant; novel; programs; transcription factor

DESCRIPTION (provided by applicant): The Molecular and Cellular Biology Core Center at the Texas Heart Institute is a multidisciplinary group of researchers focused on understanding the mechanisms of cardiovascular disease and applying that knowledge to developing innovative therapies. We are requesting startup funds for a newly independent investigator. Dr. Jun Wang, who will be joining our Core Center this summer. Dr. Wang's research program in the Core Center will focus on the role ofthe SUMO post-translational modification pathway in development of congenital heart diseases. THI is committed to providing Dr. Wang the resources and support necessary to build a successful research career, and in turn, Dr. Wang's experience and expertise will benefit other research groups in the Core Center and THI as a whole. The Molecular and Cellular Biology Core Center at the Texas Heart Institute is dedicated to understanding cardiovascular disease at a molecular level, and applying that knowledge to developing innovative therapies. Our newly independent investigator. Dr. Jun Wang, will study genetic and molecular aspects of congenital heart defects.

德克萨斯心脏研究所的分子和细胞生物学核心中心是一个多学科的研究小组，专注于了解心血管疾病的机制，并将这些知识应用于开发创新疗法。我们正在申请启动资金给一个新的独立调查员。王军博士将于今年夏天加入我们的核心中心。王博士在核心中心的研究项目将集中在SUMO翻译后修饰途径在先天性心脏病发展中的作用。THI致力于为王博士提供必要的资源和支持，以建立一个成功的研究事业，反过来，王博士的经验和专业知识将有利于核心中心和THI作为一个整体的其他研究小组。 德克萨斯心脏研究所的分子和细胞生物学核心中心致力于在分子水平上了解心血管疾病，并将这些知识应用于开发创新疗法。我们新的独立调查员。王军博士将研究先天性心脏病的遗传和分子方面。