Integrated Health Sciences Facility Core

摘要/摘要(综合健康科学核心) M-Leead的使命是加快研究，确定环境暴露的影响 在脆弱的生命阶段，并促进将研究成果转化为 缓解慢性病。为支持这项任务，M-Leead综合健康科学核心 (IHSC)使用综合的多学科方法促进多方向的翻译研究 目的是促进人们对环境暴露在生活中的影响的理解- 慢性病风险课程。在这次相互竞争的更新中，我们重组了IHSC，并 合并了以前的环境统计核心，以最大限度地提高效率和整合 职能重叠。IHSC的一个新组成部分是#年的环境健康实践小组 负责监督推广到州和地区的专业实践。IHSC特定 目标是：1)促进基础科学、机械学和毒理学之间的相互作用， 人口科学、临床研究和实践专业人员通过可搜索的、基于网络的 信息亭(M-Leead储存库亭)、年度讲习班和每周研讨会；2)至 优化我们的大量人类和动物标本和数据资源的价值和利用 通过M-Leead Repository Kiosk进行环境健康研究；以及3)促进健全研究 设计、高质量的样本收集、严格的统计分析以及 通过咨询促进环境研究的统计方法和合作 服务、研讨会和研讨会。IHSC核心的一个显著特征是我们的服务不是 与特定技术相关的。相反，IHSC提供了一个关键的联动功能，促进 翻译奖学金和多方向的利益相关者伙伴关系。我们提供咨询服务 确保研究设计、暴露评估、实验室分析和 分析方法，对建立和最大限度地利用人和 动物生物库。我们利用了由中心成员领导的NIH支持的丰富研究集， 通过M-Leead存储库Kiosk涵盖广泛的暴露和生命阶段 提供关于这些定义明确的人群中的研究机会的信息，并 动物研究及其相关数据和生物信息库。在统计方面，IHSC 开发和咨询尖端统计方法，以促进环境健康。IHSC 旨在通过主办两个年度讲习班，促进向实践和政策的转化，其中一个重点是 一个是环境统计，一个是环境健康实践。

SUMMARY/ABSTRACT (Integrated Health Sciences Core) M-LEEaD’s mission is to accelerate research that defines the impact of environmental exposures during vulnerable life stages and to promote translation of research findings to interventions that mitigate chronic disease. In support of this mission, the M-LEEaD Integrated Health Sciences Core (IHSC) promotes multi-directional translational research using integrated multi-disciplinary approaches with the goal of advancing understanding of the impact of environmental exposures across the life- course on risk of chronic disease. In this competing renewal, we have restructured the IHSC and have incorporated the former Environmental Statistics Core in order to maximize efficiency and integrate overlapping functions. A new component of the IHSC is the environmental health practice team in charge of overseeing outreach to the state and regional professional practice. The IHSC specific objectives are: 1) to facilitate interaction between basic, mechanistic and toxicological science, population sciences, clinical research and practice professionals through the searchable, web-based information kiosk (the M-LEEaD Repository Kiosk), annual workshops and weekly seminars; 2) to optimize the value and utilization of our large human and animal specimen and data resources for environmental health research through the M-LEEaD Repository Kiosk; and 3) to promote sound study design, quality specimen collection, and rigorous statistical analysis, as well as the development of statistical methods and collaborations to advance environmental research through our consultation services, seminars, and workshops. A distinctive feature of the IHSC core is that our services are not related to a specific technology. Rather, the IHSC provides a critical linkage function promoting translational scholarship and multi-directional stakeholder partnerships. We provide consulting services to ensure quality of research designs, exposure assessment, laboratory analyses, and analytic methods, with specific guidance on establishing and maximizing utilization of human and animal biobanks. We capitalize on the rich set of NIH supported studies led by center members that encompass a wide range of exposures and life-stages through the M-LEEaD Repository Kiosk providing information about research opportunities within these well-defined human population and animal studies, and their associated data and bio-repositories. On the statistical front, the IHSC develops and consults on cutting-edge statistical methods to advance environmental health. The IHSC aims to facilitate translation to practice and policy by hosting two annual workshops, one focused on environmental statistics and one focused on Environmental Health Practice.