Translational Research Training in Sleep Medicine

描述（由申请人提供）：这是T32 HL082610-04“睡眠医学转化研究培训”的第一个竞争性续期申请。该培训计划的目的是培养下一代临床和基础睡眠研究人员在睡眠医学的转化方法。我们的理念是，当睡眠医学的研究培训内容具有转译性、师资具有多学科性、结果可衡量且以能力为基础时，它是最有效的。在最初的3年半时间里，我们在运行这个项目上吸取了宝贵的经验教训，并取得了初步的成功，这得到了我们外部咨询委员会（EAB）的赞扬。在我们最初的8名博士后中，有1人获得了K奖，另外4人已经或将在未来6个月内提交。总的来说，他们在培训期间/之后发表了39篇同行评议的手稿，正在印刷或提交，以及36篇摘要。我们的10名医学生已经提交了6篇摘要，并发表了一篇第一作者的同行评审论文。我们系统地审查了我们的项目，并由学员、大学咨询委员会（UAB）和EAB进行评估。基于这些评估，我们对培训计划和招聘策略提出了具体的修改建议。培训计划包括两个部分：1)为从肺医学、精神病学、神经病学和内科项目招募的医学博士，以及通过跨学科生物医学研究生项目、临床心理学实习和流行病学研究生项目在全国和当地招募的博士毕业生提供2-3年的博士后培训奖学金。我们建议在06- 10年度维持4名受奖人的计划规模。2)医学生的研究经历，包括两个途径：a)暑期研究项目；B)贯穿4年医学院的纵向“学术项目”。我们建议每年招收4名医学学生参加暑期项目，4名学生参加纵向学术项目。博士后和医学生学员受益于多元化，多学科的培训师资；来自匹兹堡大学进行睡眠研究的优秀资源；以及强有力的机构支持，包括临床与转化科学研究所和学术职业发展办公室的项目。我们采用多种策略来招聘多元化、多学科的学员。博士后培训计划采用具体的、可量化的培训里程碑，强调指导研究；出版物;职业发展奖项的制定；以及必修课和选修课，包括负责任的研究行为。医科学生的训练同样强调科学推理和专注的、有指导的研究。持续评估是该计划的组成部分，包括UAB和EAB的输入。具体方案和机构努力的目的是征聘代表性不足的少数民族受训人员和残疾人。

DESCRIPTION (provided by applicant): This is the first competing renewal application of T32 HL082610-04, "Translational Research Training in Sleep Medicine." The aim of this training program is to train the future generation of clinical and basic sleep researchers in a translational approach to sleep medicine. Our philosophy is that research training in sleep medicine is most effective when its content is translational, its faculty multidisciplinary, and its outcomes measurable and competency-based. During our initial 31/2 years, we have learned valuable lessons on running this program and have enjoyed early success, which was commended by our External Advisory Board (EAB). Of our initial 8 postdoctoral fellows, one has received a K award, and four others have or will submit within the next 6 months. In aggregate, they have 39 peer-reviewed manuscripts published, in press, or submitted, and 36 abstracts during/after their training. Our 10 medical students have submitted 6 abstracts and published one first-authored peer-reviewed paper. We have systematically examined our program with evaluations from the trainees, a University Advisory Board (UAB), and EAB. Based on these evaluations, we propose specific modifications in the training program and in our recruitment strategies. The training program includes two components: 1) A 2-3 year postdoctoral training fellowship for MD scientists recruited from pulmonary medicine, psychiatry, neurology, and internal medicine programs and PhD graduates recruited nationally and locally through the Interdisciplinary Biomedical Graduate Program, clinical psychology internships, and the epidemiology graduate program. We propose to maintain the current program size of four fellows for Years 06- 10. 2) Research experiences for medical students, which comprise two pathways: a) a summer research program; b) a longitudinal "scholarly project" running through 4 years of medical school. We propose to enroll 4 medical students each year in the summer program, and 4 students in the longitudinal scholarly project. Postdoctoral and medical student trainees benefit from a diverse, multidisciplinary Training Faculty; from outstanding resources for conducting sleep research at the University of Pittsburgh; and from strong institutional support, including programs within the Clinical and Translational Science Institute and the Office of Academic Career Development. We use multiple strategies to recruit diverse, multidisciplinary trainees. The postdoctoral training program employs specific, quantifiable training milestones emphasizing mentored research; publications; the development of career development awards; and required and elective didactic coursework including responsible conduct of research. Medical student training likewise emphasizes scientific reasoning and focused, mentored research. Ongoing evaluation is an integral component of the program, and includes UAB and EAB input. Program-specific and institutional efforts are aimed at the recruitment of underrepresented minority trainees and individuals with disabilities.