SWOG Statistics and Data Management Center

描述（由申请人提供）：SWOG统计和数据管理中心（SDMC）在SWOG指导和参与临床试验的总体使命中发挥着至关重要的作用，这些临床试验将导致癌症的有效治疗和预防，并改善癌症患者的生活质量 患者和幸存者。SDMC在临床试验的设计、实施、监测、分析和解释方面提供统计领导和数据管理专业知识 和转化医学研究。SDMC的主要目标包括：a）设计和实施统计学上严格和有效的临床试验; B）仔细监测正在进行的试验，并使用最先进的统计分析方法分析和解释研究结果; c） 在临床试验设计和分析中进行统计方法研究，以及转化医学研究的分析; d）开发系统并利用技术，以高质量和及时地收集，审查，存储和检索临床和生物学数据; e）教育SWOG研究人员和其他肿瘤学研究专业人员前沿科学设计，统计技术和数据管理方法; f）评估有效收集特定类型患者数据的新策略，包括电子病历（EMR和基于网络的方法）;以及g）通过为NCTN的努力（如指导委员会和工作组）提供丰富的经验和领导，成为NCTN的动态成员。SWOG SDMC为NCTN内SWOG的目标做出了有意义的贡献，提供了可推广的，高质量和有效的策略，可供其他临床试验组织和研究人员在进行肿瘤学临床试验和相关生物学研究分析时使用。

DESCRIPTION (provided by applicant): The SWOG Statistical and Data Management Center (SDMC) plays a vital role in SWOG's overall mission to direct and participate in clinical trials tht will lead to effective treatment and prevention of cancer and to improve quality of life for cancer patients and survivors. The SDMC provides statistical leadership and data management expertise in the design, implementation, monitoring, analysis and interpretation of clinical trials and translational medicine studies. Key SDMC goals include the following: a) to design and implement statistically rigorous and efficient clinical trials; b) to carefully monitor ongoing trils and use state-of-the-art statistical analysis methods to analyze and interpret study results; c) to conduct statistical methods research in clinical trial design and analysis, and the analysis of translational medicine studies; d) to develop systems and utilize technologies for high quality and timely collection, review, storage and retrieval of clinical and biologic data; e) to educate SWOG investigators and other oncology research professionals in leading edge scientific design, statistical techniques and data management methods; f) to evaluate novel strategies for the efficient collection of specific types of patient data including electronic medical record (EMR and web-based methods; and g) to be a dynamic member of the NCTN by providing a wealth of experience and leadership for NCTN endeavors such as steering committees and working groups. The SWOG SDMC contributes meaningfully to the goals of SWOG within the NCTN to provide generalizable, high quality and efficient strategies that can be used by other clinical trials organizations and researchers in the conduct of oncology clinical trials and analysis of associated biologic studies.