NAVBO Workshops at Vascular Biology 2017

血管生物学2017 发育血管生物学和遗传学研讨会 (组织者：加州大学旧金山分校的布莱恩·布莱克和北卡罗来纳大学教堂山的维多利亚·鲍奇) 和 血管基质生物学与生物工程研讨会 (组织者：多伦多大学克雷格·西蒙斯和华盛顿大学杰西卡·瓦根赛尔) 2017年10月15日至19日 Asilomar会议场地，太平洋格罗夫，加利福尼亚州 首席调查员：布莱恩·布莱克 项目摘要/摘要 近年来，血管生物学领域经历了信息量的爆炸式增长。鉴于这笔财富 在信息方面，越来越需要进行讨论和跨学科的思想交流。血管 在过去的十年里，生物学已经发展成为一个主要的跨学科领域，它影响着许多 人类的主要疾病，包括动脉粥样硬化、高血压、癌症、神经疾病、糖尿病、 中风和血液系统疾病。导致这些病理的许多关键细胞事件概括起来 发生在血管发育过程中的过程，由遗传学、血管细胞、细胞外 矩阵和生物物理力。发育生物学、遗传学、矩阵之间的重要交集 生物学和生物工程不仅对血管疾病有重大影响，而且对干细胞生物学也有重大影响， 血管分化和再生。第七届NAVBO发育血管生物学与遗传学 研讨会将首次与NAVBO血管基质生物学和 生物工程研讨会，现已进入第六期。这次联合会议将把科学家和 共同感兴趣的是了解血管形成过程在发育过程中，这是如何 信息与病理状态有关，以及如何利用这些信息进行再生。这个节目是 在这两个领域感兴趣的主题中包括最新的未发布信息，并 在每个领域和这些以前分开的领域的交叉点整合新颖的新兴主题。 在这项申请中，我们申请资金，以部分支持这两个跨学科的国际研讨会， 它将汇集来自学术和私营部门的研究人员，博士后研究员，以及 来自不同领域的研究生进行了为期五天的紧张讨论和学习。这次会议 将于2017年10月15日至19日在加利福尼亚州太平洋格罗夫的Asilomar会议场地举行。我们有 汇集了一批演讲者，他们反映了发育生物学、遗传学、矩阵生物学、 以及生物工程，因为它们与血管系统有关。此外，大约一半的演讲者在 研讨会将从提交的摘要中挑选出来，以获取这些学科中最新的未发表作品。 大部分的抽象陈述将来自早期调查人员和受训人员。我们的目标是促进 在不同的调查小组之间进行高级别的思想交流，包括那些直接参与 翻译研究。我们已经包括了生物工程和血管治疗的联合会议，以 促进参与基础和临床/转化性研究的研究人员之间的互动。这次会议 寻求可能的治疗方法来改善广泛的病理状态， 包括发育缺陷、动脉粥样硬化、高血压、癌症、心肌梗死和中风。

Vascular Biology 2017 Developmental Vascular Biology and Genetics Workshop (Organizers: Brian Black, UCSF and Victoria Bautch, UNC-Chapel Hill) and Vascular Matrix Biology and Bioengineering Workshop (Organizers: Craig Simmons, University of Toronto and Jessica Wagenseil, Washington University) October 15-19, 2017 Asilomar Conference Grounds, Pacific Grove, California Principal Investigator: Brian Black Project Summary/Abstract The field of vascular biology has experienced an explosion of information in recent years. In light of this wealth of information, there is an increased need for discussion and interdisciplinary exchange of ideas. Vascular biology has evolved over the past decade as a major cross-disciplinary field that impacts on a wide number of major human diseases, including atherosclerosis, hypertension, cancer, neurological disorders, diabetes, stroke, and hematological disorders. Many of the key cellular events that lead to these pathologies recapitulate processes that take place during vascular development, guided by genetics, vascular cells, the extracellular matrix, and biophysical forces. This important intersection between developmental biology, genetics, matrix biology, and bioengineering not only has major implications for vascular disease, but also for stem cell biology, vascular differentiation, and regeneration. The seventh NAVBO Developmental Vascular Biology and Genetics Workshop will be held concurrently for the first time ever with the NAVBO Vascular Matrix Biology and Bioengineering Workshop, now in its sixth presentation. This joint conference will bring together scientists with the common interest of understanding the process of blood vessel formation in development, how this information pertains to pathological states, and how it can be exploited for regeneration. The program was developed to include the latest unpublished information in topics of interest in both of these fields and to integrate novel, emerging themes in each area and at the intersection of these previously separate fields. In this application we request funds to partially support both of these interdisciplinary, international workshops, which will bring together investigators from the academic and private sectors, postdoctoral fellows, and graduate students from diverse fields of study for five days of intense discussion and study. The conference will be held at the Asilomar Conference Grounds in Pacific Grove, CA from October 15-19, 2017. We have assembled a roster of speakers that reflects the leaders in developmental biology, genetics, matrix biology, and bioengineering as they pertain to the vasculature. In addition, approximately half of the speakers at the workshops will be chosen from submitted abstracts to capture the latest unpublished work in these disciplines. The majority of abstract presentations will be from early stage investigators and trainees. It is our aim to foster a high-level exchange of ideas among a diverse group of investigators, including those directly involved in translational research. We have included joint sessions on bioengineering and vascular therapeutics to facilitate interactions among researchers involved in basic and clinical/translational research. The conference seeks insight into possible therapeutic approaches to ameliorate a broad spectrum of pathological states, including developmental defects, atherosclerosis, hypertension, cancer, myocardial infarction, and stroke.