Integration of a Sensory Feedback Implant with Myoelectric Prosthetic Hands

7.项目摘要/摘要 接受严重上肢截肢的人失去了显著的灵活性和功能，因为假肢装置 与生理手相比，替代失去的肢体的自由度更少，并且缺乏感觉 反馈。在过去的二十年里，多功能假手的发展速度加快了 然而，市面上出售的设备都不能提供感官反馈。这个项目的目标是 设计、开发和测试可提供生理上适当感觉的假肢系统 使用多功能假手进行反馈。简而言之，这个项目计划为 上肢截肢者。 我们将调查两个假设。1)使用假肢系统的肢体丧失者，包括 肌电多自由度假手和生理上适当的感觉反馈将显著 与进行日常生活活动相比，进行日常生活活动可以更快地提高表现和学习速度 没有感觉反馈的相同任务。2)在以下情况下感到生理上合适的反馈的人 使用肌电多自由度假体进行日常生活活动将体验到 与没有体验感官反馈的人相比，具体化的感觉。 为了回答这些假设，将实现三个具体目标。在具体目标1中，一个先进的 假肢系统将被开发出来，以检验这些假说。这个假体将整合 将以下技术应用到无缝实时假肢系统中：1)表面肌电(EMG) 传感器，2)肌电姿态控制算法，3)六自由度仿生假手，4)Numatac 指尖传感器(Synouch LLC.洛杉矶，加利福尼亚州)，以及5)用于刺激周围神经和 感觉反馈的传递。在具体目标2中，将进行日常生活能力测试，以便 量化有感觉和无感觉的高级假肢系统的功能改善 反馈。最后针对具体目标3、假体植入措施(PIC)和控制瓶颈指标 (CBI)结果测量将被用来量化受试者所经历的具体化。 该项目将极大地提高假肢技术。科学知识和临床实践 对上肢截肢者的尊重都将得到推进。我们相信这个系统可以减少 通过提高假体使用者执行功能性任务的能力从而降低他们的排斥率 共病，如健侧肢体累积性创伤障碍。我们还预计，这个系统将 通过减少幻肢疼痛和增加生活质量来改善截肢者的生活质量 假体的化身。由于幻肢疼痛而造成的时间和金钱成本是一项巨大的医疗保健 关注，任何减轻这一负担的方法都将是一项巨大的成就，能够提供 为退伍军人和非退伍军人提供更好的医疗保健。提议的协作是一个独特的机会 在退伍军人保健系统内，可以积极影响临床保健和康复 退伍军人。

7. Project Summary/Abstract People with major upper limb amputation lose significant dexterity and function because the prosthetic devices that replace the lost limb contain fewer degrees of freedom than the physiological hand and lack sensory feedback. The development of multi-functional prosthetic hands has accelerated over the past two decades however none of the commercially available devices provide sensory feedback. The goal of this project is to design, develop, and test a prosthetic limb system which provides physiologically appropriate sensory feedback with a multi-functional prosthetic hand. In short, this project plans to recreate the sense of touch for persons with upper-limb amputation. Two hypotheses will be investigated. 1) Persons with limb loss using a prosthetic system including a myoelectric multi-DoF prosthetic hand and physiologically appropriate sensory feedback will significantly improve performance and learn quicker when performing activities of daily living compared to performing the same tasks without sensory feedback. 2) Persons feeling physiologically appropriate feedback when performing activities of daily living with a myoelectric multi-DoF prosthesis will experience an increased sensation of embodiment compared to persons not experiencing the sensory feedback. Three specific aims will be accomplished in order to answer the hypotheses. In specific aim 1, an advanced prosthetic limb system will be developed in order to test the hypotheses. This prosthesis will integrate the following technologies into a seamless, real-time prosthetic limb system: 1) surface electromyographic (EMG) sensors, 2) the myoelectric postural control algorithm, 3) the six DoF Bebionic prosthetic hand, 4) Numatac fingertip sensors (Syntouch LLC. Los Angeles, CA), and 5) FINE for stimulation of peripheral nerves and delivery of sensory feedback. In Specific Aim 2, tests of activities of daily living will be performed in order to quantify the functional improvements of the advanced prosthetic limb system with and without sensory feedback. Finally in Specific Aim 3, the prosthesis incorporation measure (PIC) and control bottleneck index (CBI) outcome measures will be used to quantify the embodiment experienced by the subjects. This project will dramatically improve prosthetic limb technology. Scientific knowledge and clinical practice with respect to persons with upper limb amputation will both be advanced. We believe this system could reduce the rejection rates of prosthetic users by improving their ability to perform functional tasks and thereby reduce comorbities such as cumulative trauma disorders in the sound-side limb. We also expect that this system will improve the quality of life in people with an amputation by reducing phantom limb pain and increasing the embodiment of the prosthesis. The cost in time and money due to phantom limb pain is a massive healthcare concern, and any method to reduce this burden would be a monumental achievement in the ability to provide better healthcare for Veterans and non-Veterans alike. The proposed collaboration is a unique opportunity within the VA health care system that can positively impact the clinical healthcare and rehabilitation of Veterans.