Molecular Basis of Immunity - Kirschstein - NRSA

描述(申请人提供)：未来的免疫学家必须理解基础和临床免疫学，以有效地利用现代研究工具追求新的 关于免疫介导性疾病和传染病及其发病机制的知识，以及针对免疫介导性疾病的新疫苗和疗法的开发。就免疫学及其与传染病的关系对科学家和内科科学家进行培训 以及其他相关学科，如病理学、生物化学、细胞生物学和生物技术，将对免疫科学的未来至关重要。为了促进免疫学领域知识的传播，免疫学培训方案的目标是为4名博士后和2名博士后研究员提供基础和研究培训，免疫学教员由20名讲师组成。该项目的独特之处在于，它包括来自俄克拉荷马大学健康科学大学和俄克拉荷马医学研究基金会的教师，以及对微生物和宿主免疫学的强烈关注。参与培训的教师在免疫学培训计划中强调的4个子学科中尤其强大，包括1)对病原体的反应，2)淋巴细胞发育和信号，3)炎症，4)自身免疫。多年来，教员们在OUHSC园区进行了互动，形成了一个特别适合培养具有凝聚力的分子免疫学博士后和博士后研究员的网络。该计划从国内和国际来源招募学生和研究员，拥有强大的NIH资助的研究项目，并拥有新的教员和设施，所有这些都在培训中营造了一种卓越的氛围。博士前学生在完成实验室轮换和资格考试后，有资格参加培训计划。免疫学培训计划将通过免疫学课程和务虚会，为博士后和博士后学员提供4个子学科的深入丰富。强烈鼓励博士后研究员参加课程，并指导博士后学生，以增强他们的免疫学经验。免疫学培训计划咨询和遴选委员会挑选博士后和博士后学员，并以咨询身份行事。自2001年9月1日该计划开始以来，该计划的目标正在实现，为受训人员提供卓越的研究、免疫学课程作业、免疫学静修和免疫学杂志俱乐部课程。一年一度的免疫学互动静修和免疫学杂志俱乐部课程有效地将博士后和博士后研究员以及培训人员聚集在一起，创造了一个促进卓越的环境。我们的计划一直是，并将继续是重要的培训，为未来的职业生涯免疫学。

DESCRIPTION (provided by applicant): The immunologist of tomorrow must appreciate both basic and clinical immunology to effectively utilize modern tools of research in the pursuit of new knowledge about immune mediated and infectious diseases and their pathogenesis as well as for development of new vaccines and therapies against immune-mediated diseases. Training the scientist and the physician-scientist in immunology and its relationship to infectious diseases as well as to other related disciplines such as pathology, biochemistry, cell biology and biotechnology will be crucial for the future of immunological sciences. To facilitate the distribution of knowledge in the field of immunology, the Immunology Training Program goals are to provide fundamental and research training to 4 predoctoral and 2 postdoctoral fellows with an immunology faculty of 20 preceptors. The program is unique in that it encompasses faculty from the University of Oklahoma Health Sciences and the Oklahoma Medical Research Foundation as well as its strong focus on microbial as well as host immunology. The participating training faculty are particularly strong in the 4 subdisciplines emphasized in the Immunology Training Program, which include 1) Responses to Pathogens, 2) Lymphocyte Development and Signaling, 3) Inflammation, and 4) Autoimmunity. The faculty preceptors have interacted on the OUHSC campus for years, forming a network that is particularly suited to train a cohesive group of pre and postdoctoral fellows in molecular immunology. The program recruits students and fellows from national and international sources, has strong NIH funded research programs, and has new faculty and facilities, all of which foster an atmosphere of excellence in training. The predoctoral students are eligible for the training program after completion of their lab rotations and qualifying exam. The Immunology Training Program will provide in-depth enrichment in the 4 subdisciplines to the pre and postdoctoral trainees through immunology classes and retreats. Postdoctoral fellows are strongly encouraged to take coursework and to mentor predoctoral students to enhance their immunology experience. The Immunology Training Program advisory and selection committee selects the pre and postdoctoral trainees and acts in an advisory capacity. Since the beginning of the program September 1, 2001, the objectives of the program are being met to provide excellence in research, immunology course work, an immunology retreat, and an immunology journal club class for the trainees. The yearly interactive immunology retreat as well as the Immunology Journal Club class have been effective in bringing the pre and postdoctoral fellows together with the training faculty in an environment that fosters excellence. Our program has been and will continue to be important to prepare trainees for future careers in immunology.