Sex Differences in TAAR1: A New Participant in Methamphetamine Abuse

补助金P51OD011092的5年续期要求为ONPRC的项目提供资金，这些项目支持 生物医学研究。该应用程序反映了对跨学科研究的战略关注，以优化 非人灵长类(NHP)模型的使用和发展。本申请的目的是：1)进行 最先进的研究，其中NHP是唯一适合于解决人类健康问题的研究2) 为开展跨学科生物医学研究提供区域和国家资源，特别是 因为它与国家卫生政策有关。3)追求最高标准的人道和负责任的动物护理。4)提供 为那些准备进入研究和生物教学职业的人提供研究培训和经验。至 为了实现这些目标，需要在八个大的领域提供支持。 1)行政部门为ONPRC的所有方面提供所需的行政和服务支持。 单位包括：主任办公室；行政事务；商务事务；设施；信息 系统、研究图书馆和研究安全。2)动物服务。单位包括：资源、设施、 和手术；病理学服务；组织分配计划；外科服务；行为 服务；研究、教育和培训；临床医学；NHP资源(肥胖、灵长类老龄化、 传染病、时间交配繁殖和日本猕猴)。3)核心科学服务。单位 包括：辅助生殖技术、内分泌技术、流式细胞术、影像与形态学、 分子和细胞生物学、分子病毒学、磁共振成像和灵长类遗传学。4) 科学部分包括支持科学部门(神经科学、病理生物学和免疫学、 生殖与发育科学与糖尿病、肥胖与代谢)和交叉学科 研究项目(衰老生物学、儿童早期健康与发育、灵长类遗传学研究)。 5)试点项目方案。6)改进与现代化。7)外展和社区参与。8) 以NPRC联盟为基础的活动。

The 5-year renewal for Grant P51OD011092 requests funding for programs at the ONPRC that support biomedical research. The application reflects a strategic focus on interdisciplinary research to optimize the use and development of nonhuman primate (NHP) models. The aims of this application are to: 1) Conduct state-of-the-art research for which NHPs are uniquely suited for solutions to human health problems 2) Provide a regional and national resource for the conduct of interdisciplinary biomedical research, especially as it relates to NHPs. 3) Pursue the highest standards of humane and responsible animal care. 4) Provide research training and experience for those preparing to enter research and biological teaching careers. To accomplish these aims, support is requested in eight broad areas. 1) Administration provides the administrative and service support required for all aspects of the ONPRC. Units include: the Director's Office; Administrative Services; Business Services; Facilities; Information Systems; Research Library; and Research Safety. 2) Animal Services. Units include: Resources, Facilities, and Operations; Pathology Services; the Tissue Distribution Program; Surgical Services; Behavioral Services; Research, Education and Training; Clinical Medicine; NHP Resources (Obese, Primate Aging, Infectious Disease, Time-mated Breeding, and Japanese macaque). 3) Core Science Services. Units include: Assisted Reproductive Technology, Endocrine Technology, Flow Cytometry, Imaging & Morphology, Molecular & Cellular Biology, Molecular Virology, Magnetic Resonance Imaging, and Primate Genetics. 4) Scientific Components include support for Scientific Divisions (Neuroscience, Pathobiology & Immunology, Reproductive & Developmental Sciences and Diabetes, Obesity & Metabolism) and the Interdisciplinary Research Programs (Biology of Aging, Early Childhood Health & Development, Primate Genetics Research). 5) Pilot Project Program. 6) Improvement & Modernization. 7) Outreach and Community Engagement. 8) NPRC Consortium-Based Activities.