ENNCF - Rodent Behavior Core

摘要 啮齿动物行为核心(RBC)的任务是提供计划、执行和分析 使用小鼠和大鼠进行与神经系统疾病和中风相关的行为实验。加拿大皇家银行致力于 为Emory研究社区提供高质量的啮齿动物行为方法和 关联的资源。像其他ENNCF核心一样，RBC是由机构支持(中心 神经退行性疾病，人类遗传学系，埃默里大学神经科学倡议， 和医学院)，以满足神经科学研究人员日益增长的需求 在其他情况下不可用。NINDS资助的研究人员占RBC的比例非常高 用户(25个PI中有14个)，并且目标与ENNCF的目标匹配，因此决定将RBC添加到 这个P30应用程序。 将RBC加入ENNCF将为Emory NINDS调查人员提供优先和补贴 获得RBC提供的多种啮齿动物行为分析和外科服务。因为没有 NINDS资助的单个实验室拥有由NINDS提供的一系列行为任务、专业知识和设备 对于他们的研究项目的成功，这种访问将是至关重要的。RBC的加入将把一个完整的 在这些调查人员的指尖上提供一系列行为服务，而成本仅为 获得进行啮齿动物行为研究的设备和训练有素的人员。 RBC的主要目标是：(1)提供最先进的啮齿动物行为测试 设备和新兴技术，(2)规划、执行和分析方面的专门知识和指导 啮齿动物行为研究实验；(3)优秀的研究环境，提供 基础设施、教育和资源，以促进调查人员和核心之间的合作。这些 加拿大皇家银行实施的目标已被证明能够刺激基础研究领域的多学科研究和创新 和转化性神经科学。

SUMMARY The mission of the Rodent Behavioral core (RBC) is to provide planning, execution, and analysis of behavioral experiments relevant to neurological diseases and stroke using mice and rats. The RBC strives to provide the Emory research community ready access to high quality rodent behavioral methodologies and associated resources. Like other ENNCF cores, the RBC was seeded with institutional support (the Center for Neurodegenerative Disease, Department of Human Genetics, the Emory University Neuroscience Initiative, and the School of Medicine), to meet the growing needs of neuroscience investigators with services that had not been available otherwise. With NINDS funded investigators comprising a very high percentage of RBC users (14 out of 25 PIs), and well-matched goals with those of the ENNCF, it was decided to add the RBC to this P30 application. Addition of the RBC to the ENNCF will provide Emory NINDS investigators with preferred and subsidized access to the multiple rodent behavioral assays and surgical services offered by the RBC. Because no individual NINDS-funded laboratory has the array of behavioral tasks, expertise, and equipment offered by the RBC, this access will be vital to the success of their research programs. The inclusion of the RBC will put a full range of behavioral services at the fingertips of these investigators at a fraction of the cost it would take to acquire the equipment and trained personnel to conduct rodent behavioral research. The primary objectives of the RBC are to provide: (1) access to state-of-the-art rodent behavioral testing equipment and emerging technologies, (2) expertise and guidance in the planning, execution, and analysis of rodent behavioral research experiments, and (3) an outstanding research environment that provides infrastructure, education and resources to foster collaborations between investigators and cores. These objectives implemented by the RBC have proven to stimulate multidisciplinary research and innovation in basic and translational neuroscience.