K24 Clinical research in Antimicrobial Resistance and Hospital Epidemiology

描述（由申请人提供）：目前的提案是对先前资助的K24的竞争性更新。主要研究者Anthony Harris博士是一名传染病医生和流行病学家。在他14年的教师，他已经超过125手稿出版。在这些手稿中，他是50多个的第一或最后作者。这些手稿大多集中在以下研究领域：抗菌素耐药性，医院流行病学，感染控制，以及抗菌素耐药性研究中的流行病学和统计方法。从他指导的时候到现在，他的学员已经有超过450个出版物。101份出版物为学员/导师出版物。33名学员中有18人目前正在从事学术医疗事业。在K24的最初五年里，他成功地完成了所有提出的目标，并指导了六名教师的职业发展奖。在K24期间，他有超过46篇出版物，其中44篇涉及学员。他目前的资金水平包括NIH R 01，AHRQ R 01，CDC合同，经常要求额外的分包合同，NIH合同的共同研究员和两个行业赞助的研究赠款。K24的更新对于他继续指导新出现的耐药性，医疗保健相关感染和医院流行病学领域的年轻研究人员并继续发展他的研究至关重要。他将参加额外的课程，以帮助他的研究进入集群随机试验，基因组流行病学，比较有效性研究和微生物组和耐药性的研究领域。哈里斯实现这些目标的关键是保护时间;没有K24更新，他将不得不参加更多的传染病服务，并进行更多的医院流行病学和质量改进，以增加针对他的工资报销。

DESCRIPTION (provided by applicant): The current proposal is a competitive renewal of a previously funded K24. The Principal Investigator, Dr. Anthony Harris, is an infectious disease physician and epidemiologist. During his fourteen years as faculty, he has had more than 125 manuscripts published. Among these manuscripts, he has been first or last author on more than 50. Most of these manuscripts have been focused in the following research areas: antimicrobial resistance, hospital epidemiology, infection control, and epidemiological and statistical methods in the study of antimicrobial resistance. His mentees have had over 450 publications from the time of his mentoring to the present. 101 publications have been mentee/mentor publications. Eighteen of 33 mentees are presently pursuing academic medical careers. In the initial five years of his K24, he successfully completed all proposed aims and mentored six faculty's career development awards. During the K24 period, he had over 46 publications of which 44 involved mentees. His current level of funding includes an NIH R01, an AHRQ R01, a CDC contract that has frequent requests for additional sub-contracts, a co-investigator on an NIH contract and two industry-sponsored research grants. Renewal of this K24 is critical to his desire to continue to mentor young investigators in the emerging areas of antibiotic-resistance, healthcare-associated infections and hospital epidemiology and to continue to evolve his research. He will take additional coursework to help move his research into the areas of cluster-randomized trials, genomic epidemiology, comparative effectiveness research and the study of the microbiome and antibiotic-resistance. The protected time is critical to Dr. Harris achieving these goals; without the K24 renewal, he will have to attend more on the infectious disease service and perform more hospital epidemiology and quality improvement in order to increase reimbursement directed towards his salary.