Effect of Banning Menthol Flavorant on Cigarette and e-Cigarette Use

项目摘要 随着《家庭吸烟预防和烟草控制法案》的通过，美国食品 美国药品监督管理局(FDA)禁止用水果或糖果调味的香烟，但特别排除了薄荷醇 从这个禁令中解脱出来。随着FDA最近将其权力扩展到电子烟(即电子烟)， 制定关于调味剂(包括薄荷醇)可获得性的法规的能力将扩展到这些 产品也是如此。由于目前关于电子烟中薄荷醇的味道的信息有限 影响总体烟草使用，但几乎没有科学依据可供制定法规 关于非卷烟形式烟草中的薄荷醇调味剂。拟议的研究将获得初步的 关于免除或包括电子烟的薄荷醇禁令可能会如何影响整体 烟草使用。在这项研究中，吸食薄荷醇香烟的人将在6周内被分配到三组中的一组 条件：1)模拟禁止薄荷醇香烟但不禁止薄荷醇电子烟的条件；2)条件 模拟禁止薄荷醇香烟和薄荷醇电子烟；以及3)薄荷醇 任何一种产品都不禁止(即，控制条件)。参与者将能够使用符合以下条件的任何产品 在他们的随机组中可用，所有参与者都将获得医用尼古丁，如果他们 决定完全戒烟。在六周的时间里，烟草产品的使用，戒烟的动机， 将评估戒烟尝试的次数，以及对薄荷醇禁令的支持情况。将使用来自这项试点研究的数据 计划进行更大规模的研究，研究电子烟中的薄荷醇味道如何影响烟草产品的使用模式和 吸烟者中的毒物暴露。这项工作是创新的，因为以前的研究没有评估影响 监管香烟中的薄荷醇，同时豁免电子烟。它的重要之处在于它开始提供一个 评估电子烟中的薄荷醇香料是否应该受到与电子烟不同的监管的科学依据 香烟。

Project Summary Following the passage of the Family Smoking Prevention and Tobacco Control Act, the United States Food and Drug Administration (FDA) banned cigarettes flavored with fruit or candy, but specifically excluded menthol from this ban. With the FDA recently extending its authority to electronic cigarettes (i.e., e-cigarettes), the ability to enact regulations regarding the availability of flavorants (including menthol) will extend to these products as well. As there is limited information currently available on how menthol flavoring in e-cigarettes affects overall tobacco use, there is little scientific basis available upon which to formulate regulations regarding menthol flavorant in non-cigarette forms of tobacco. The proposed study will obtain preliminary information regarding how a menthol ban that either exempts or includes e-cigarettes is likely to affect overall tobacco use. In this study, menthol cigarette smokers will over a 6 week period be assigned to one of three conditions: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes; 2) a condition simulating a ban on both menthol cigarettes and menthol e-cigarettes; and 3) a condition in which menthol is not banned for either product (i.e., the control condition). Participants will be able to use any products that are available in their randomization group and all participants will have medicinal nicotine available should they decide to quit tobacco products entirely. Over the six week period, tobacco product use, motivation to quit, number of quit attempts, and support for a menthol ban will be assessed. Data from this pilot study will be used to plan larger studies examining how menthol flavor in e-cigarettes affects tobacco product use patterns and toxicant exposure among smokers. This work is innovative as previous studies have not evaluated the impact of regulating menthol in cigarettes while exempting e-cigarettes. It is significant in that it begins to provide a scientific base for evaluating if menthol flavoring in e-cigarettes should be regulated differently than in cigarettes.