Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: an RCT in Kisarawe, Tanzania
Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: an RCT in Kisarawe, Tanzania
批准号:
9750110
负责人:
Michael D Sweat
金额:
$60.99万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-15 至 2021-06-30
关键词:
AIDS preventionAcquired Immunodeficiency SyndromeAddressAffectAfrica South of the SaharaAwarenessBlood GlucoseBlood PressureCaringCatchment AreaCensusesCharacteristicsClientClinicClinicalCommunitiesConsultCounselingCountryDataDiabetes MellitusDropoutEnrollmentEpidemicExpenditureFailureFatigueGlycosylated hemoglobin AGoalsHIVHIV InfectionsHealthHealth BenefitHouseholdHuman immunodeficiency virus testHypertensionIncidenceIndividualInfectionInterventionInvestmentsKnowledgeLeadLifeMedicalPatientsPatternPersonsPilot ProjectsPoliciesPopulationPrediabetes syndromePreventionProbabilityPublic HealthQuality of lifeRandomizedRandomized Controlled TrialsRecording of previous eventsSamplingSavingsServicesSiteStigmatizationSystemTanzaniaTestingTimeViralVisitantiretroviral therapybaseburden of illnesscare costsclinically significantcohortcommunity settingcostcost effectivecost effectivenessdesigndiabetes controlefficacy testingexperiencehypertension controlhypertension treatmentimprovedinterestlow and middle-income countriesnovelprehypertensionpreventprogramsrural areascreeningsocial stigmatransmission processtreatment centertreatment programtrenduptake
中文摘要
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英文摘要
PROJECT SUMMARY / ABSTRACT
HIV testing is often shunned in community settings due to the stigma of HIV-centric services. Our recent pilot
study strongly suggest that integration of a package of screening that include HIV, diabetes, and hypertension
hold promise of substantially increasing the uptake of HIV testing while simultaneously providing direly needed
community screening for non-communicable disease (NCDs) like diabetes and hypertension, which
themselves are at epidemic levels in Sub-Saharan Africa. In our pilot study we found that HIV testing almost
doubled when diabetes and hypertension screening was added. Moreover, once HIV-infected individuals are
identified, many are reluctant to enter care due to the stigma of HIV-centric care programs, and over time
attrition of clients is a serious problem undermining the clinical and public health benefits of these programs.
Our preliminary studies strongly suggest that integration of NCD care within HIV care would increase
enrollment and retention in HIV care by destigmatizing the clinics for all attendees, and by providing tangible
clinical therapies for the estimated 79% of HIV-infected clients who also have NCDs, especially those waiting
to become eligible for ART, who are also those with the highest attrition. We will assess: (a) the client
characteristics and patterns of utilization at the 6 HIV Care and Treatment Centers (CTCs) in Kisarawe District,
Tanzania; (b) trends in HIV testing; (c) history of HIV intervention (d) census data; (e) conduct community
mapping in each CTC’s catchment area; (f) consult with community leaders and Medical Officers , and (g)
match two similar CTCs . Next, one of the two CTCs will be randomized as an enhanced intervention site. At
both CTCs we will conduct community mobilization to alert community of available services. At the enhanced
intervention CTC we will also provide screening for diabetes and hypertension. The Health Center (always
adjacent to the CTC) will be assisted with treating positive NCD cases. HIV-infected clients will be referred to
the CTC at both sites, and the first 89 patients at each CTC will be enrolled in a cohort and followed for 24-
months (total N=178 across 2 clinics). Those in the cohort at the enhanced intervention CTC who are NCD
positive will have care for NCDs integrated with their HIV care. We will assess how NCD screening affects
uptake of HIV testing at the community-level over ~18-months. We will establish whether adding NCD care to
HIV care improves linkage and enrollment in HIV care. We will determine if retention in HIV care among newly
enrolled clients is enhanced over 24-months with the addition of NCD care. We will then cost all intervention
components to determine the incremental cost per added client tested for HIV, enrolled in HIV care, and
retained in HIV care by adding NCD screening and care.
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会议论文
The Evidence Project: Systematic Reviews of Critical HIV Interventions, and Disruption in HIV Services from COVID-19 in LMIC
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批准号:10275167
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项目类别:
-
资助金额:$49.24万
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财政年份:2021
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负责人:Michael D Sweat
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依托单位:
The Evidence Project: Systematic Reviews of Critical HIV Interventions, and Disruption in HIV Services from COVID-19 in LMIC
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批准号:10395612
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项目类别:
-
资助金额:$48.63万
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财政年份:2021
-
负责人:Michael D Sweat
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依托单位:
The Evidence Project: Systematic Reviews of Critical HIV Interventions, and Disruption in HIV Services from COVID-19 in LMIC
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批准号:10570851
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项目类别:
-
资助金额:$46.04万
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财政年份:2021
-
负责人:Michael D Sweat
-
依托单位:
Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: an RCT in Kisarawe, Tanzania
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批准号:9203236
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项目类别:
-
资助金额:$67.38万
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财政年份:2016
-
负责人:Michael D Sweat
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依托单位:
Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: An RCT in Kisarawe, Tanzaniz
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批准号:10449427
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项目类别:
-
资助金额:$10.88万
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财政年份:2016
-
负责人:Michael D Sweat
-
依托单位:
Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care: an RCT in Kisarawe, Tanzania
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批准号:9353480
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项目类别:
-
资助金额:$60.99万
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财政年份:2016
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负责人:Michael D Sweat
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依托单位:
Phase II RCT of Comprehensive Triaged HIV Prevention: Tanzania (Supplement)
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批准号:9076791
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项目类别:
-
资助金额:$15.05万
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财政年份:2015
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负责人:Michael D Sweat
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依托单位:
Dyadic-Based Diagnosis, Care, & Prevention for HIV Discordant Couples in Tanzania
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批准号:9119641
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项目类别:
-
资助金额:$58.61万
-
财政年份:2015
-
负责人:Michael D Sweat
-
依托单位:
Dyadic-Based Diagnosis, Care, & Prevention for HIV Discordant Couples in Tanzania
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批准号:9277597
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项目类别:
-
资助金额:$57.64万
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财政年份:2015
-
负责人:Michael D Sweat
-
依托单位:
Dyadic-Based Diagnosis, Care, & Prevention for HIV Discordant Couples in Tanzania
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批准号:8846365
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项目类别:
-
资助金额:$66.49万
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财政年份:2015
-
负责人:Michael D Sweat
-
依托单位:
Phase II RCT of Comprehensive Triaged HIV Prevention: Tanzania
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批准号:8514078
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项目类别:
-
资助金额:$53.47万
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财政年份:2012
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负责人:Michael D Sweat
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依托单位:
Phase II RCT of Comprehensive Triaged HIV Prevention: Tanzania
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批准号:8661304
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项目类别:
-
资助金额:$56.16万
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财政年份:2012
-
负责人:Michael D Sweat
-
依托单位:
Phase II RCT of Comprehensive Triaged HIV Prevention: Tanzania
-
批准号:8277702
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项目类别:
-
资助金额:$57.45万
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财政年份:2012
-
负责人:Michael D Sweat
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依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
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批准号:8015289
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项目类别:
-
资助金额:$39.11万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
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批准号:8414164
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项目类别:
-
资助金额:$37.16万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
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批准号:9237307
-
项目类别:
-
资助金额:$44.33万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
-
批准号:8992627
-
项目类别:
-
资助金额:$51.94万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
-
批准号:8607599
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项目类别:
-
资助金额:$36.32万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
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批准号:7865574
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项目类别:
-
资助金额:$42.4万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
Synthesizing HIV Behavioral Intervention Effectiveness in Developing Countries
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批准号:8215840
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项目类别:
-
资助金额:$40.26万
-
财政年份:2010
-
负责人:Michael D Sweat
-
依托单位:
海外基金