UNC Center for AIDS Research Core F Biostatistics

项目摘要/摘要--生物统计核心 生物统计核心的广泛、长期目标是提供广泛的统计支持 用于北卡罗来纳大学CFAR的艾滋病毒/艾滋病相关研究。具体目标包括：(1)提供广泛的 协作性生物统计服务；(2)发展、实施和传播创新统计 艾滋病毒/艾滋病研究方法；(3)支持CFAR优先倡议和目标；(4)促进CFAR 在北卡罗来纳州开展研究，促进CFAR之间的合作，并支持艾滋病毒/艾滋病研究网络；(5) 提供生物统计学培训、指导和教育；以及(6)参与评估和战略 计划满足北卡罗来纳大学CFAR不断变化的需求。为了实现这些目标， 生物统计核心与北卡罗来纳大学CFAR调查人员积极接触，以确定和提供必要的服务 用于艾滋病毒/艾滋病研究的高效设计、管理、分析和出版。《核心》 有助于假设的框架、研究设计的制定、赠款申请的准备， 选择最佳统计方法，并提供统计分析。艾滋病毒/艾滋病新调查人员 研究是核心服务的最高优先事项。核心还开发和实施创新 CFAR研究所需的统计方法。此外，该中心还提供培训和教育，以 CFAR研究界为调查人员配备传统和创新的统计方法 需要进行艾滋病毒/艾滋病相关研究。来自北卡罗来纳州北卡罗来纳州教育部的强有力的机构支持 生物统计使核心能够充分利用现有的基础设施、资源和与 以其在统计专业领域的专业知识而闻名的教师。企业的管理和战略规划 核心将通过与核心董事的协商、对CFAR成员的调查、内部 咨询委员会、外部咨询委员会，并通过参加CFAR务虚会。

PROJECT SUMMARY/ABSTRACT – BIOSTATISTICS CORE The broad, long-term objectives of the Biostatistics Core are to provide a wide spectrum of statistical support for HIV/AIDS-related research of the UNC CFAR. The specific aims include: (1) providing a broad spectrum of collaborative biostatistical services; (2) developing, implementing, and disseminating innovative statistical methods for HIV/AIDS research; (3) supporting priority CFAR initiatives and goals; (4) promoting CFAR research within UNC, fostering inter-CFAR collaborations, and supporting HIV/AIDS research networks; (5) providing biostatistical training, mentoring, and education; and (6) engaging in evaluation and strategic planning to address the changing needs of the UNC CFAR. To achieve these aims, members of the Biostatistics Core proactively engage with UNC CFAR investigators to identify and deliver services essential for highly productive design, management, analysis and publication of HIV/AIDS research. The Core contributes to the framing of hypotheses, development of study designs, preparation of grant applications, selection of best statistical methods, and delivery of statistical analyses. Investigators new to HIV/AIDS research receive highest priority for Core services. The Core also develops and implements innovative statistical methodologies as needed for CFAR studies. Additionally, the Core provides training and education to the CFAR research community to equip investigators with traditional as well as innovative statistical methods needed to conduct HIV/AIDS related research. Strong institutional support from the UNC Department of Biostatistics allows the Core to take full advantage of existing infrastructure, resources and contacts with faculty renowned for their expertise in specialized fields of statistics. Management and strategic planning of the Core will be guided by consultation with the Core Directors, surveys of the CFAR membership, an Internal Advisory Board, an External Advisory Board, and through participation in CFAR retreats.