2019 Carbohydrates Gordon Research Conference and Gordon Research Seminar

项目摘要 碳水化合物在人体动态平衡、免疫学、变态反应、移植、微生物和 病毒感染、宿主-微生物相互作用、癌症等问题日益受到人们的重视。然而，详细的 关于碳水化合物如何参与这些重要的生理和病理事件的信息 分子水平是有限的。在碳水化合物研究的各个领域取得了重大进展，以 弥合差距。2019碳水化合物戈登研究会议(GRC)汇聚专家和 具有不同背景和专业知识的新兴研究人员展示尖端研究进展 (大多数未发表)，并公开讨论碳水化合物领域的想法和未来方向，重点是 架起化学和生物学的桥梁，将基础科学转化为应用。为期4.5天的会议将以 30个特邀演讲，14个从提交的摘要中挑选出来的简短演讲，以及4个海报预览会议，最多可达200个 总参与人数。主要主题从碳水化合物结构和糖组分到合成策略， 碳水化合物生物合成和降解酶，以碳水化合物为基础的益生素和疗法， 免疫学和化学糖生物学、人类和微生物糖类以及宿主微生物中的碳水化合物 互动。同时，2019碳水化合物戈登研究研讨会(GRS)是一个为期1.5天的论坛，致力于 专门面向年轻科学家，在糖科学社区建立网络和职业发展 通过口头演示、职业小组讨论、研讨会和海报演示。2019年的三个具体目标 碳水化合物GRC和GRS将：1)展示尖端研究进展，促进批判性思维， 并鼓励讨论以催化碳水化合物领域的进展；2)提供令人鼓舞的 网络环境、思想自由交流和有助于塑造未来的开放讨论 碳水化合物领域的方向；以及3)促进碳水化合物领域多元化劳动力的形成 通过在会议环境中将新来者与来自不同背景的更多成熟的榜样混合在一起。 总体目标是让具有平衡性别和少数民族代表性的科学家参与并整合在 来自世界各地的不同职业阶段，在友好的环境中拥有不同的研究背景 现场会议、前沿研究演示、开放讨论、互动和休闲活动，以 推进碳水化合物领域，这将极大地促进人类健康的改善。

Project Summary The important roles of carbohydrates in human homeostasis, immunology, allergy, transplantation, microbial and viral infection, host-microbe interaction, and cancer etc. have been increasingly recognized. However, detailed information on how carbohydrates are involved in these important physiological and pathological events at the molecular level is limited. Significant advances have been made in various areas of carbohydrate research to bridge the gap. The 2019 Carbohydrates Gordon Research Conference (GRC) brings together experts and emerging investigators with diverse backgrounds and expertise to present cutting-edge research progresses (most unpublished) and openly discuss ideas and future directions in the carbohydrate field with a focus on bridging Chemistry and Biology, and translating basic science to application. The 4.5-day conference will feature 30 invited talks, 14 short talks selected from submitted abstracts, and 4 poster preview sessions with up to 200 total participants. Major topics range from carbohydrate structures and glycomics, to synthetic strategies, carbohydrate biosynthesis and degradation enzymes, carbohydrate-based prebiotics and therapeutics, immunology and chemical glycobiology, human and microbial glycomes, and carbohydrates in host-microbe interactions. Conjunctly, the 2019 Carbohydrates Gordon Research Seminar (GRS) is a 1.5-day forum dedicated exclusively to young scientists to establish network and career developments in the glycoscience community through oral presentations, career panel, workshops, and poster presentations. Three specific aims of the 2019 Carbohydrates GRC and GRS are to: 1) present cutting-edge research development, promote critical thinking, and encourage discussion to catalyze the advance of the carbohydrate field; 2) provide an encouraging environment for networking, free-exchanging of ideas, and open discussion that can help to shape the future direction of the carbohydrate field; and 3) promote the formation of a diverse workforce in the carbohydrate field by mingling new comers with more established role models from a diverse background at the conference setting. The overall goal is to engage and integrate scientists with balanced gender and minority representation at different career stages from all over the world with diverse research backgrounds in a friendly environment with on-site meeting, cutting-edge research presentation, open discussion, interaction, and leisure activities to advance the field of carbohydrates which will greatly facilitate the improvement of human health.