Diversity Action Plan for Mouse Genome Database

 描述(由申请人提供)：位于缅因州巴尔港的杰克逊实验室(JAX)提议每年为来自代表性不足群体的四名学生提供暑期研究实习机会，在NHGRI资助的小鼠基因组数据库(MGD)的研究人员的指导下，从事生物信息学和基因组学的研究项目。拟议的多样性行动计划(DAP)寻求资金，将这一成功的计划再持续四年，目标是鼓励未被充分代表的学生在基因组相关领域攻读更高的学位和职业。MGD被认为是国际科学界关于小鼠的数据库，提供高质量的综合信息，支持小鼠实验系统向人类生物学和疾病研究的转化。四名MGD DAP生物信息学实习生将被整合到现有的JAX暑期学生计划(SSP)中，这是一种国际公认的住宿研究经验，自1924年以来已指导了2100多名本科生和高中生。这个已建立的JAX项目每年招收30-40名学生，他们是通过全国范围内的竞争性申请程序挑选出来的。每个学生都会得到每周的津贴、生活津贴和旅行补助，这使他们能够放弃暑期工作，参与这种身临其境的、变革性的研究体验。除了实际操作计算和实验室工作的培训、方案撰写和结果展示，以及研究伦理和人道对待实验室动物的坚实基础外，所有SSP参与者都住在一个有40个房间的住宅里，并分享丰富的社交和娱乐活动。JAX SSP--由机构基金、私人基金会和联邦拨款支持--在多样性招聘和遴选、导师指导以及项目设计、管理和评估方面有完善的行政程序。拟议DAP的培训协调员将进行生物信息学特定多样性的招聘，支持实习生培训，并在随后的职业发展中跟踪项目校友。DAP首席调查员将监督DAP的所有规划和实施，包括导师指导和项目管理。JAX提供了一个激励的环境，在这个环境中，来自不同背景的有动力、有才华的本科生可以学习科学探究的基础知识，为研究进步做出贡献，并在智力和个人成长方面取得长足进步，这将指导他们进行职业选择和终身学习。SSP在少数民族(西班牙裔、非裔美国人、土著美国人、太平洋岛民/夏威夷人)的参与方面有着良好的记录，这是通过在全国范围内有针对性的招募、SSP网站和校友网络实现的。2014年暑期学生计划有11名代表不足的少数族裔学生(29%)，其中7名(18%)是第一代大学生或经济困难的学生。 公共卫生报告：拟议的生物信息学和基因组学暑期实习将为学生提供机会，在杰克逊实验室NHGRI资助的小鼠基因组数据库(MGD)计划的研究人员的指导下，为积极的研究项目做出贡献。MGD数据库是专门为促进使用鼠标作为模型系统而设计的，以便在基因组规模、数据驱动的生物医学研究时代实现关于人类健康和疾病的新发现。我们专注于从代表性不足的群体中招收学生，以确保未来科学、医疗和教育劳动力的多样性。这次身临其境的研究体验的校友将是科学大使，他们具有坚实的伦理基础，了解数据科学为推进基础人类疾病研究所面临的挑战和前景，并热衷于分享他们对科学的热爱，以造福社会。

 DESCRIPTION (provided by applicant): The Jackson Laboratory (JAX) in Bar Harbor, Maine, proposes a summer research internship for four students per year from underrepresented groups to pursue research projects in bioinformatics and genomics, under the mentorship of investigators of the NHGRI-funded Mouse Genome Database (MGD). The proposed Diversity Action Plan (DAP) seeks funding to continue this successful program for four more years, with a goal of encouraging underrepresented students to pursue advanced degrees and careers in genomics-related fields. MGD is regarded as the international scientific community database for mouse, providing high quality, integrated information that supports the translation of the mouse experimental system to the study of human biology and disease. The four MGD DAP bioinformatics interns will be integrated into the existing JAX Summer Student Program (SSP), an internationally recognized residential research experience that has mentored more than 2,100 undergraduates and high school students since 1924. This established JAX program annually hosts 30- 40 students who are selected through a competitive nationwide application process. Each student receives a weekly stipend, subsistence allotment, and travel assistance that enables them to forgo summer jobs and participate in this immersive, transformational research experience. In addition to training in hands-on computational and laboratory work, proposal writing and results presentation, and solid grounding in research ethics and the humane treatment of lab animals, all SSP participants lodge together in a 40-room residence and share abundant social and recreational activities. The JAX SSP--supported by institutional funds, private foundations, and federal grants--has well-established administrative procedures for diversity recruitment and selection, mentor guidance, and program design, management, and evaluation. The Training Coordinator for the proposed DAP will pursue bioinformatics-specific diversity recruitment, support intern training, and track program alumni during their subsequent career development. The DAP Principal Investigator will oversee all DAP planning and implementation, including mentor guidance and program administration. JAX offers a stimulating environment in which motivated, talented undergraduates from diverse backgrounds can learn the fundamentals of scientific inquiry, contribute to research progress, and make great strides in intellectual and personal growth that will guide them in career choices and lifelong learning. The SSP has a proven track record of underrepresented minority (Hispanic, African American, Native American, Pacific Islander/Hawaiian) participation, which is achieved through targeted recruiting nationwide, the SSP website, and alumni networking. The 2014 Summer Student Program had 11 underrepresented minority students (29%), including 7 participants (18%) who were first-generation college students or were economically disadvantaged. PUBLIC HEALTH RELEVANC: The proposed summer internship in bioinformatics and genomics will offer students the opportunity to contribute to active research projects with mentorship from the investigators in the NHGRI-funded Mouse Genome Database (MGD) program at The Jackson Laboratory. The MGD database is designed specifically to facilitate use of the mouse as a model system to enable new discoveries about human health and disease in the age of genome-scale, data-driven biomedical research. We focus on recruiting students from underrepresented groups to ensure diversity in the scientific, medical, and education workforces of the future. The alumni from this immersive research experience will be science ambassadors with a solid grounding in ethics, an appreciation for the challenges and promises of data science for advancing basic human disease research, and zeal to share their love of science for the benefit of society.