Nebraska Research Network in Functional Genomics

生物信息核心实验室 项目摘要 生物信息学核心在NE-INBRE项目的整体成功中发挥了关键作用， 获得资源、技术、服务，并向网络成员提供使用 生物信息学中的计算和数据分析工具。在过去的五年里，使用高通量 包括下一代测序（NGS）在内的技术已成为NE-INBRE的常见技术 investigators.因此，有一个巨大的需求，发展计算和生物信息学 用于收集、处理、存储和分析大规模数据集的基础设施。具有平行 在不断变化的实验技术的发展，新的生物信息学算法和工具需要 开发或采用，以满足研究社区日益增长的数据分析需求。鉴于 由于这种复杂性，单个机构在本地开发和维护复杂的 生物信息学的基础设施和技术专长。该生物信息学核心的主要目标是开发 这样的环境，技术，工具和服务，并使其可供所有成员在NE-INBRE 网络核心的主要目标包括为未来需求开发尖端基础设施 同时继续支持和培训NE-INBRE学者和调查人员使用资源， 技术.生物信息学核心将配备提供所需的基础设施，获得资源， 为NE-INBRE网络成员提供技术支持、教育和指导机会。

Bioinformatics Core Project Summary The Bioinformatics Core has served as a key player in the overall success of the NE-INBRE project by facilitating access to resources, technology, services, and providing training to the network members in the use of computational and data analysis tools in bioinformatics. Over the past five years, the use of high-throughput technologies including next-generation sequencing (NGS) has become a commonplace by the NE-INBRE investigators. Consequently, there has been a tremendous need for developing computational and bioinformatic infrastructure for the collection, processing, storage, and analysis of large-scale datasets. With parallel developments in the ever-changing experimental technologies, new bioinformatic algorithms and tools need to be developed or adopted to meet the growing data analysis needs of the research community. Given the nature of this complexity, it is extremely challenging for individual institutions to locally develop and maintain sophisticated infrastructure and technical expertise in bioinformatics. The primary goal of this Bioinformatics Core is to develop such environment, technology, tools, and services and make them accessible to all members in the NE-INBRE network. The main objectives of the Core include the development of cutting-edge infrastructure for future needs while continuing to support and train NE-INBRE Scholars and investigators in the use of resources and technologies. The Bioinformatics Core will be equipped to provide the needed infrastructure, access to resources, technical support, education and mentoring opportunities for the NE-INBRE network members.