Modality specific naming assessment across the age span

项目摘要 在说话时说出正确的单词的能力对社交、学术和职业都是至关重要的 功能正常。不幸的是，在许多神经性疾病中，单词查找或“命名”可能会受损 涉及皮质功能的障碍，因此，命名评估是 神经心理评估。由于命名受颞叶区域的调节，命名评估起着重要作用 在评估颞叶癫痫(TLE)患者中起着关键作用。我们在这方面的初步工作解决了 癫痫命名评估的多重缺陷，历史上仅限于视觉对象 命名。通过皮质映射，我们发现了支持基于命名的皮质区域之间的分离 视觉提示与听觉提示的对比。与此相适应，听觉命名和视觉命名互补性测试 我们的开发和标准化(发表于2003年)被发现有助于对皮质进行定侧和定位 与癫痫发作相关的功能障碍，从而有助于难治性癫痫的术前评估 病人。在这项初步工作的基础上，我们开发并标准化了这些措施的儿科版本，以及 将很快完成老年人、年龄、听力和视觉命名测试的标准化 56比95。重要的是，最初的测试只包括55岁以下的成年人，没有充分考虑到 刺激物的寿命和规范数据有限。我们继续收到大量关于 这些测试；然而，原始测试不符合当前标准，在高质量方面留下了严重差距 为16-55岁进行命名评估，这是绝大多数癫痫手术进行的时候。基于 在多年的原始测试经验中，儿科和老年人的命名测试有了很大的改进 关于心理测量学属性和标准数据。老年人测试中的刺激物也非常 非常适合青少年和年轻人。利用我们的实验室基础设施和经验， 拟议的项目将把测试和标准数据升级到16-55岁的现行标准，以及 在左侧(主要)和右侧TLE患者中验证这些措施，使继续使用听觉和 青壮年癫痫患者的视觉命名，在语言衰退的背景下更早发现 退化过程，更广泛地说，通过以下方式为青少年提供高质量的命名评估 任何神经认知障碍的成年后期。

Project Summary The ability to produce the correct words while speaking is critical for social, academic and occupational functioning. Unfortunately, word finding or “naming” can become impaired in a number of neurological disorders involving cortical function, and thus, naming assessment is an integral component of neuropsychological evaluation. As naming is mediated by the temporal lobe region, naming assessment plays a critical role in the evaluation of temporal lobe epilepsy (TLE) patients. Our initial work in this area addressed multiple shortcomings in naming assessment in epilepsy, which historically, was limited to visual object naming. Through cortical mapping, we found a dissociation between cortical areas that support naming based on visual versus auditory cues. In line with this, the auditory naming and complementary visual naming tests we developed and standardized (published in 2003) were found to assist in lateralizing and localizing cortical dysfunction associated with seizure onset, thereby aiding the presurgical evaluation for refractory epilepsy patients. Based on this initial work, we developed and standardized pediatric versions of these measures, and will soon complete standardization of auditory and complementary visual naming tests for older adults, ages 56-95. Importantly, the original tests which included only adults up to age 55, did not adequately consider longevity of the stimuli, and the normative data were limited. We continue to receive numerous requests for these tests; however, the original tests are not up to current standards, leaving a critical gap in high quality naming assessment for ages 16-55, when the vast majority of epilepsy surgeries are performed. Based on years of experience with the original measures, the pediatric and older-adult naming tests are vastly improved with regard to psychometric properties and normative data. The stimuli in the older-adults tests are also very well-suited for adolescents and younger adults. Capitalizing on our laboratory infrastructure and experience, the proposed project will upgrade the tests and normative data to current standards for ages 16-55, and validate these measures in left (dominant) and right TLE patients, enabling continued use of auditory and visual naming in younger adults with epilepsy, earlier detection of language decline in the context of degenerative processes, and more generally, provide high quality naming assessment for adolescence through late adulthood for any neurocognitive disorder.