Training in Precision Environmental Health Sciences

数据摘要/摘要 精密环境健康科学（TPEHS）计划的跨学科培训是一项联合倡议 贝勒医学院（Baylor College of Medicine）和德克萨斯大学休斯顿学院健康科学中心（University of Texas Health Science Center at Houston School of 公共卫生（UTH-SPH）。基因与环境（GxE）交叉点的研究有助于 环境和公共卫生领域，大大提高了我们对环境因素的认识 和遗传因素。基因组学和环境健康研究正在产生越来越大的 数据集，阐明了今天的环境健康研究人员需要能够将大数据 他们的研究。TPEHS的目标是培养下一代环境健康科学家 在遗传学，环境健康和数据科学（GxExD）的接口工作。培训计划是 该中心的精确环境健康在华盛顿州，由项目主任博士谢丽尔步行者。 该中心为TPEHS提供了强有力的机构支持，并为这一联合培训计划提供了“基地”。 TPEHS计划的目标是为学员1）获得遗传学，环境， 健康和数据科学; 2）精通将GxExD概念整合到研究中; 3）获得 利用GxExD培训实现下一个职业目标所需的技能和工具。该计划将 在第一年支持2名博士前和2名博士后学员，增加到3名博士前和3名博士后学员/年 然后博士生的核心课程包括环境教育课程 健康/毒理学，遗传学和数据科学以及精确度综合概念基础课程 环境卫生。这种教学培训还辅之以职业发展活动、 负责任地进行研究和严谨性和再现性，以及计划/网络机会 （包括同行辅导），以改善培训环境并在受训人员中建立凝聚力。在 除了基础课程外，博士后培训还包括基于行业的网络机会 与健康与环境科学研究所（HESI）和/或通过赠款准备学术生涯- 写作研讨会和提交K99/R 00申请。在这两个领导层在TVB和UTH-SPH有 承诺为该计划的学员提供四个额外的名额，增加学员队伍的规模 并将申请人的范围扩大到美国公民以外。TPEHS是一个独特的机会， 生物医学科学家在GxExD研究和利用协作环境和研究强国 德州医学中心科学界的一员在课程结束时，学员将有一个深刻的 了解跨学科的GxExD研究，证明有能力进行独立的研究， 这是一个具有挑战性的多学科领域，需要有效的准备精确的环境卫生 明天的研究者

PROGRAM SUMMARY / ABSTRACT The interdisciplinary Training in Precision Environmental Health Sciences (TPEHS) program is a joint initiative of Baylor College of Medicine (BCM) and the University of Texas Health Science Center at Houston School of Public Health (UTH-SPH). Research at the intersection of genes and the environment (GxE) has contributed to the fields of environmental and public health and significantly advanced our knowledge of environmental factors and genetic contributors to disease. Genomics and environmental health research are producing ever-larger data sets, illuminating the need for today's environmental health researchers to be able to incorporate big data into their research. The goal of the TPEHS is to train the next generation of environmental health scientists working at the interface of genetics, environmental health and data science (GxExD). The training program is aligned with the Center for Precision Environmental Health at BCM, led by Program Director Dr. Cheryl Walker. This Center provides strong institutional support for the TPEHS and a “home base” for this joint training program. TPEHS Program Objectives are for trainees to 1) acquire fundamental knowledge in Genetics, Environmental Health, and Data Science; 2) become proficient at integrating concepts of GxExD into research; and 3) gain the necessary skills and tools to leverage GxExD training to achieve their next career objective. The Program will support 2 pre- and 2-post-doctoral trainees in Year 1, increasing to 3 pre- and 3 post-doctoral trainees/year thereafter. The core curriculum for PhD students includes didactic coursework in Environmental Health/Toxicology, Genetics, and Data Science and a Foundations Course on Integrative Concepts of Precision Environmental Health. This didactic training is complemented by career development activities, training in Responsible Conduct of Research and Rigor and Reproducibility, and programmatic/networking opportunities (including peer-to-peer mentoring) that enhance the training environment and build cohesion among trainees. In addition to the Foundations Course, postdoctoral training includes the opportunity for industry-based networking with the Health and Environmental Sciences Institute (HESI) and/or preparation for academic careers via grant- writing workshops and submission of a K99/R00 application. Leadership at both BCM and UTH-SPH have committed to providing four additional slots for trainees in the Program, increasing the size of the trainee cohort and broadening the applicant pool beyond US citizens. The TPEHS is a unique opportunity to cross-train biomedical scientists in GxExD research and leverage the collaborative environment and research powerhouse of the Texas Medical Center scientific community. At the end of the program, trainees will have a deep understanding of inter-disciplinary GxExD research, demonstrated ability to carry out independent research in this challenging multidisciplinary area, and the preparation needed be effective precision environmental health researchers of tomorrow.