Cancer Researchers in Nanotechnology (CRIN)

7.项目摘要/摘要： 该培训计划试图解决两个问题：(1)尽管在癌症生物学方面取得了所有研究进展 并将这些发现应用于临床，癌症治疗在延长生命方面取得的成功有限。 工程方法已经开始显示出希望，但缺乏训练有素的调查人员。 癌症研究和工程/材料科学。(2)目前的癌症博士和博士后培训 研究的重点是让受训人员成为独立的研究人员，但它并没有提供全面的 年轻科学家的一套技能，当他们在学术界开始他们的职业生涯时，将与 小型/初创制药或设备公司，甚至可能在重新进入之前在一家小公司工作 学术界。在解决这两个问题上存在协同作用，因为年轻的科学家在 纳米技术和癌症生物学处于有利地位，可以与小公司合作或在小公司工作 专注于癌症的制药或医疗设备公司。拟议的计划将为受训人员提供 平衡地结合(A)全面的癌症生物学、工程学和创业教育 培训，(B)实验室经验，由一名基础科学癌症研究人员和临床/翻译人员双重指导 (C)通过让受训人员与小企业企业家一起工作而学到的实用技能 直接和/或准备和辩护研究提案。将有两个培训轨道：一个是针对以下学员的 计划最初在初创公司工作，并为计划最初在学术界工作的实习生提供服务。

7. PROJECT SUMMARY/ABSTRACT: This training program seeks to address two issues (1) In spite of all of the research advances in cancer biology and application of these discoveries to the clinic, cancer therapies have had limited success in prolonging life. Engineering approaches have begun to show promise, but there is a dearth of investigators who are trained in both cancer research and engineering/materials science. (2) Current PhD and postdoctoral training in cancer research focuses on preparing trainees to be independent researchers, but it doesn't provide a comprehensive set of skills for young scientists who, when starting their careers in academia, will be working closely with small/startup pharmaceutical or device companies or who may even work in a small firm before reentering academia. There is a synergy in addressing both issues since young scientists with cross training in nanotechnology and cancer biology are well positioned to work in collaboration with or work in small pharmaceutical or medical device companies focused on cancer. The proposed program will provide trainees with a balanced combination of (a) a comprehensive cancer biology, engineering, and entrepreneurship didactic training, (b) laboratory experience dual-mentored by a basic science cancer researcher and clinical/translational cancer faculty, and (c) practical skills learned by having the trainees work with small business entrepreneurs directly and/or prepare and defend research proposals. There will be two training tracks: one for trainees who plan to initially work in startup companies and one for trainees who plan to initially work in academia.