Biostatistics & Informatics Shared Resource

生物统计学和信息学共享资源-项目摘要 生物统计学和信息学共享资源（BISR）在以下研究活动中发挥着重要作用： 堪萨斯大学癌症中心（KUCC）通过支持KUCC研究人员的数据科学需求。 BISR由布鲁克L.弗里德利是一位有成就的生物统计学家，长期致力于 跨学科合作，并包括另外八名患有专门癌症的教职员工 生物统计学研究专长。BISR通过提供研究设计方面的专业知识来协助KUCC研究人员， 统计监督和分析、临床研究信息学和数据管理、电子数据 收集、生物信息学、统计基因组学和研究者发起的临床试验。 BISR由教师和工作人员组成，他们的不同专业知识和技能涵盖生物统计学领域， 生物信息学和信息学。这三个领域之间的相当大的重叠使研究人员能够工作 通过单一共享资源满足所有数据收集、分析和统计分析需求。的协同作用 包括“数据科学”的领域之间的联系使BISR能够支持广泛的质量 服务，并以及时和具有成本效益的方式。为了支持KUCC成员的研究活动， 该资源的具体目标是：1）提供研究设计、统计支持和专业知识; 2）提供 生物信息学和统计遗传学支持和专业知识; 3）为数据收集提供信息学支持 4）开发和支持正在进行的研究，使技术，平台和工具;以及 5)教育KUCC的学生，研究员和教职员工关于数据科学和可复制的研究想法 和癌症研究中使用的方法。 在CCSG赠款的最后一个周期，BISR服务被用于 101名KUCC成员提交了240份赠款申请（随后获得的赠款占总数的34% 支持BISR教职员工）和545个涉及数据科学专业知识的项目。作为一个重要的共享 作为KUCC的资源，BSR利用了大量的机构支持，仅要求11%的支持， CCSG。

Biostatistics & Informatics Shared Resource – Project Summary The Biostatistics and Informatics Shared Resource (BISR) plays an essential role in the research activities of the University of Kansas Cancer Center (KUCC) by supporting the data science needs of KUCC investigators. The BISR is led by Brooke L. Fridley, an accomplished biostatistician with a long-standing commitment to cross-disciplinary collaborations, and includes eight additional faculty members with specialized cancer biostatistics research expertise. The BISR assists KUCC investigators by providing expertise in study design, statistical oversight and analyses, clinical research informatics and data management, electronic data collection, bioinformatics, statistical genomics and investigator initiated clinical trials. The BISR consists of faculty and staff, whose diverse expertise and skill sets span the areas of biostatistics, bioinformatics and informatics. The considerable overlap between these three areas allow researchers to work with a single shared resource for all their data collection, analytics and statistical analysis needs. The synergy between the areas that encompass “data science” enables the BISR to support a wide-range of quality services, and in a timely and cost-effective manner. To support the research activities of KUCC members, the specific aims of this resource are to: 1) provide study design and statistical support and expertise; 2) provide bioinformatics and statistical genetics support and expertise; 3) provide informatics support for data collection and management; 4) develop and support on-going research enabling technologies, platforms and tools; and 5) educate students, fellows and faculty members of KUCC on data science and reproducible research ideas and methods used in cancer research. During the last cycle of the CCSG grant, BISR services were used by 101 KUCC members for 240 grant submissions (with subsequent awarded grants providing 34% of total support for BISR faculty and staff) and 545 projects involving data science expertise. As an essential shared resource for KUCC, the BSR leverages substantial institutional support and requests only 11% support from the CCSG.