2020/2022 Auditory System GRC/GRS

项目总结 听觉GRC和GRS一起提供了独特的功能组合，包括：研究的广度，切割- 边缘强调，来自所有级别和不同子领域和地点的调查人员的混合，亲密的规模和 延长了讨论时间。其中一些特征源于听力研究领域的独特品质和 其他人则来自戈登会议的既定性质和非常成功的形式。 2020年会议的总主题利用方法和理论创新，重点是 对听觉系统功能的预防和恢复有较全面的认识。这些主题 被广泛地解释为跨越对构成限制和破坏的基本和病理机制的研究 正常的听觉功能到治疗障碍的翻译努力和新的治疗和生物学 旨在恢复功能的干预措施。2022年会议的总主题尚未确定，但将 使用类似的方法，整合所有层次的听觉系统的研究。 会话将从其基本的外围机制遍历听觉系统到中央通路， 多感官整合和行为输出。该节目将包括正常的病因和病理学。 听觉功能，疾病和创伤造成的功能障碍，以及创新的预防方法 听力损失和听力损失后恢复功能。调查人员将突出不同的模型系统和 修复受损听觉系统的技术、临床相关性和潜在的翻译工具， 包括干细胞治疗、毛细胞再生、基因治疗和下一代人工耳蜗术。 我们将设计一些能够吸引不同背景的科学家的课程。我们 努力突出不同的模型系统，从斑马鱼到人类，以及从分子和 遗传到系统和行为。在整个会议期间，我们将包括一系列广泛的演讲，重点是 中枢性和外周听神经科学研究，并将包括2020年更广泛的主题 和2022年听觉GRC。我们的目标是鼓励异常高的出席率在整个会议和交叉- 不同学科之间的受精。对于听觉GRS，演讲将从提交的摘要和 以一位受邀的导师-参与者的主旨演讲为基础。此外，指导是一个积极的组成部分 是GRS的。主旨演讲者以及GRC组织者将出席非正式和正式会议 讨论包括由NIDCD的一名代表参加的研究资助会议和职业会议， 以在不同领域工作的个人为特色，如学术界、工业界、出版业和政策界。

PROJECT SUMMARY Together the Auditory GRC & GRS offer a unique combination of features, including: breadth of research, cutting- edge emphasis, mingling of investigators from all ranks and diverse sub-fields and locales, intimate size and extended discussion time. Some of these features arise from unique qualities of the hearing research field and others from the Gordon Conferences’ established nature and highly successful format. The general theme of the 2020 meeting leverages innovation in approaches and theory, focusing on an integrated understanding of preventing loss and recovering function of the auditory system. These topics are broadly construed to span research on basic and pathological mechanisms that pose limitation and destroy normal auditory function to translational efforts to treating disorders and novel therapeutic and biological interventions to recover function. The general theme of the 2022 meeting has not yet been determined, but it will use a similar approach of integrating research across all levels of the auditory system. Sessions will traverse the auditory system from its fundamental peripheral mechanisms to the central pathways, multi-sensory integration, and behavioral output. The program will include the etiology and pathology of normal auditory function, disruption of function through disease and trauma, and innovative approaches to preventing hearing loss and to recovering function after loss. Investigators will highlight different model systems and technologies, clinical relevance, and potential translational tools for repairing damaged auditory systems, including stem cell therapy, hair cell regeneration, gene therapy, and next generation cochlear implants. We will design sessions that have something that will appeal to scientists with diverse backgrounds. We endeavor to highlight different model systems, from zebrafish to humans, and technologies from molecular & genetic to systems and behavior. Throughout the sessions we will include a broad mix of talks that focus on studies of central and peripheral auditory neuroscience and will include the broader thematic topics for the 2020 and 2022 Auditory GRC. Our goal is to encourage unusually high attendance throughout the meeting and cross- fertilization across disciplines. For the Auditory GRS, talks will be selected from submitted abstracts and anchored by a keynote address by an invited mentor-participant. In addition, mentoring is an active component of the GRS. The keynote speaker, as well as the GRC organizers, will be available for informal and formal discussions including a research funding session, featuring a representative from NIDCD, and a career session, featuring individuals working in diverse fields, such as academia, industry, publishing and policy.