Interventional and Translational Core

干预和翻译核心(ITC)的总体目标是提供专业知识、工具和基础设施 协助调查人员制定、实施和评估文化适宜性 干预措施。我们的目标是创造有关糖尿病预防和管理的新知识 和心脏代谢性疾病，重点是减少健康差距。ITC的3个具体目标是： 1.为糖尿病预防和管理的干预发展提供专家咨询(例如， 优化体重、锻炼/体力活动、服药依从性和/或血糖控制的干预措施)。 这一专门知识将有助于将基础科学成果转化为有效性和有效性测试 临床试验和社区试验中的干预措施。 2.为评估和数据获取提供专门知识和工具，包括测量、质量控制、 为预防和管理糖尿病的研究提供质量保证和分析支持。服务包括 关于饮食、体力活动、移动卫生技术、行为、心理社会和 社会文化参数、建筑环境、生活质量和文化能力。 3.制定并促进文化上适当的战略，以加强招募和留住少数群体 糖尿病相关研究中服务不足的人群，重点是非裔美国人和 农村社区。 这些核心服务基于受资助的刚果民主共和国调查人员的明确需求，方法将依赖于 经过验证的、最先进的方法，高度重视数据质量控制。ITC将利用 现有的招聘和基于社区的研究的基础设施，并在 可用于刚果民主共和国研究基地的干预措施的制定、实施和评估，促进 创新和推进糖尿病防治科学。

The overall goal of the Interventions and Translation Core (ITC) is to provide expertise, tools, and infrastructure to assist investigators with the development, implementation, and evaluation of culturally appropriate interventions. Our objective is to create new knowledge regarding the prevention and management of diabetes and cardiometabolic disease, with an emphasis on reducing health disparities. The ITC’s 3 specific aims are to: 1. Provide expert consultation for intervention development in diabetes prevention and management (e.g., interventions to optimize weight, exercise/physical activity, medication adherence, and/or glycemic control). This expertise will facilitate translation of basic science findings into efficacy and effectiveness testing of interventions in both clinic-based and community-based trials. 2. Provide expertise and tools for evaluation and data acquisition, including measurement, quality control, quality assurance, and analytic support, for research to prevent and manage diabetes. Services include methods and tools regarding diet, physical activity, mobile health technology, behavior, psychosocial and sociocultural parameters, built environment, quality of life, and cultural competence. 3. Design and facilitate culturally appropriate strategies to enhance the recruitment and retention of minorities and underserved populations in diabetes-related research studies, with emphasis on African American and rural communities. These core services are based on the expressed needs of funded DRC investigators, and methods will rely on validated, state-of-the-art approaches with a high priority placed on data quality control. The ITC will leverage existing infrastructure for recruitment and community-based research and make cutting edge expertise in intervention development, implementation and evaluation available to the DRC research base, promoting innovation and advancing the science of diabetes prevention and management.