Imaging and Radiation Oncology Core (IROC) Group

成像和放射肿瘤学(IROC)小组的主要目标是 提供科学和技术专业知识，以纳入适当的、综合的 影像和放射治疗的质量保证(QA)和图像数据管理 (RT)在国家临床试验网络(NCTN)进行的适用试验中 计划和其他由NCI资助的临床试验小组(NCORP和ETCTN)。体能 IROC质量保证中心分布在4个主要地点，并以行政方式组织 通过美国放射学会(ACR)。质量保证中心包括IROC 休斯顿、俄亥俄IROC、罗德岛IROC和费城IROC。先进性 位于圣路易斯华盛顿大学的技术QA中心(ATC)将提供 根据需要向IROC提供他们的专业知识和咨询服务。IROC利用 QA中心的现有基础设施和专业知识目前为 NCI的临床试验计划。工作流程、流程和信息系统已经 在综合愿景中考虑到最佳做法和标准的情况下得到加强 在NCI的临床试验中。成像和RT之间的相互依赖关系是 协同消除重复服务，优化高效高效 工作流程。IROC的一个主要优势是制定一致的标准 NCTN、NCORP和ETCTN所有成像和RT方面的操作程序 (NCI组)，并促进成像和RT患者病例数据集的无缝流动 在整个网络中。IROC的组织结构允许交付广泛的 成像和RT QA服务，包括现场鉴定；试验设计支持； 认证；数据管理(治疗前和治疗后病例审查)；以及案例 回顾一下。使用信息技术基础设施来协调IROC NCI组临床服务、数据收集、评估和管理 审判。IROC实施的计划可确保一致的高质量成像和RT 跨NCTN参与站点的规划/交付。IROC成员与 每个网络组内的NCI、NCI小组和疾病/医疗保健委员会 提供最佳有效的影像和放射治疗核心服务。IROC集团将 分析前瞻性/回溯性获得的质量保证数据及其可能存在的相关性 临床试验结果，以更好地确定适当的QA活动并确定其优先顺序 使他们在临床试验中受益最大化。

The primary objective of the Imaging and Radiation Oncology (IROC) Group is to provide scientific and technical expertise for incorporation of appropriate, integrated quality Assurance (QA) and image data management for both imaging and radiotherapy (RT) in applicable trials conducted by the National Clinical Trials Network (NCTN) Program and other NCI funded clinical trial groups (NCORP and ETCTN). The physical IROC QA Centers are distributed in 4 main locations and are administratively organized through the American College of Radiology (ACR). The QA Centers include IROC Houston, IROC Ohio, IROC Rhode Island, and IROC Philadelphia. The Advanced Technology QA Center (ATC) located at Washington University, St. Louis will provide their expertise and consultation services to IROC as needed. IROC capitalizes on existing infrastructure and expertise at QA centers currently providing services to the NCI’s clinical trial programs. Work flows, processes and information systems have been enhanced taking into account the best practices and standards in an integrated vision across NCI’s clinical trials. The interdependencies between imaging and RT are synergized eliminating duplication of services and optimizing efficient and effective workflows. A major strength of IROC is the development of consistent standard operating procedures for all imaging and RT aspects of the NCTN, NCORP and ETCTN (NCI Groups) and to facilitate a seamless flow of imaging and RT patient case datasets across the networks. IROC’s organizational structure allows the delivery of a broad array of imaging and RT QA services including Site Qualification; Trial Design Support; Credentialing; Data Management (Pre- and Post-treatment Case Review); and Case Review. An information technology infrastructure is used that harmonizes IROC services, data collection, assessment and management for the NCI Groups’ clinical trials. IROC implements programs that assure consistent high quality imaging and RT planning/delivery across the NCTN participating sites. IROC members collaborate with the NCI, NCI Groups, and disease/modality committees within each Network Group to provide an optimum and effective imaging and RT core service. The IROC Group will analyze QA data obtained prospectively/retrospectively and the correlation it might have with clinical trial outcomes to better determine and prioritize appropriate QA activities that maximize their benefit to clinical trials.