Advanced Research Training in Otolaryngology

摘要 物理科学家和学术医生在发现和随后的翻译中发挥着关键作用。 研究进展到改善患者的医疗保健，这是NIH路线图的核心过程。因此，我们认为， 专门和密集的研究培训对于培养下一代临床科学家至关重要。 耳鼻喉科医生最有可能从事NIDCD使命领域的研究，包括听力、平衡、声音， 沟通障碍，味觉，嗅觉和相关的细胞生物学。这次竞争性更新的目标是 继续在医学培训的不同阶段提供研究经验，让医学生参与， 住院医师和住院后研究员。具体而言，我们建议支持：1）12个月的博士预科 两名对耳鼻喉科和传播科学感兴趣的医学生的研究经验， 鼓励追求包括研究培训和最终学术生涯的住院医师; 2）18 每年为一名耳鼻喉科住院医师提供为期几个月的博士后研究培训，以定义和开发 研究兴趣继续作为一个学术教员;和3）12个月的博士后后， 每年为一名实习生提供住院医师奖学金，以补充其临床专科培训，并为 作为临床科学家的学术生涯。前体已从国际公认的 密歇根大学的教师，由基础科学，转化和临床研究人员组成， 耳鼻咽喉头颈外科、神经科、精神科、 家庭医学、人类遗传学、生物医学工程和生物与材料科学。大焦点 包括听力损失和听力恢复的机制，头颈肿瘤学，组织 生物工程、神经再生、3D打印、应用人工耳蜗研究和聋人健康服务 和重听患者。每个学员将有学术耳鼻喉科教师作为主要或 二级导师重点将放在项目设计/翻译潜力，多学科 合作、授权、手稿开发和研究建议和发现的介绍。 将提供机会参加校外或校内会议或相关的教育课程 学员选择的研究学科该部门的研究计划和设施 耳鼻咽喉头颈外科和克雷斯吉听力研究所是世界上最好的听力研究所之一。 世界，代表着一股强大的力量。密歇根临床与健康研究所（MICHR）， 由临床转化科学奖资助，赞助优秀的临床培训机会， 研究以及临床研究的资源。此外，密歇根大学还拥有广泛的 在临床和基础研究方面的投资，包括众多的核心设施，以及主要的交叉研究， 部门中心。

ABSTRACT Physician-scientists and academic physicians play key roles in discoveries and the ensuing translation of research advances into improved health care for patients, a process central to the NIH Roadmap. Therefore, dedicated and intensive research training is essential to developing the next generation of clinician-scientists. Otolaryngologists are most likely to undertake research in the NIDCD mission areas of hearing, balance, voice, communication disorders, taste, smell, and related cellular biology. The goal of this competitive renewal is to continue to provide research experiences at different stages of medical training, involving medical students, resident physicians, and post-residency fellows. Specifically, we propose to support: 1) 12-month predoctoral research experience for two medical students interested in otolaryngology and the communication sciences, to encourage pursuit of residencies that include research training and, ultimately, academic careers; 2) 18 months of postdoctoral research training for one otolaryngology resident per year, to define and develop a research interest to be continued as an academic faculty member; and 3) 12-month postdoctoral post- residency fellowship for one trainee per year to complement their clinical subspecialty training and prepare for academic careers as clinician-scientists. Preceptors have been selected from the internationally-recognized faculty at the University of Michigan, consisting of basic science, translational and clinical researchers with primary appointments in the departments of Otolaryngology-Head & Neck Surgery, Neurology, Psychiatry, Family Medicine, Human Genetics, Biomedical Engineering and Biologic & Materials Sciences. Major focuses of research include the mechanisms of hearing loss and hearing restoration, head and neck oncology, tissue bioengineering, nerve regeneration, 3D printing, applied cochlear implant research and health services for deaf and hard of hearing patients. Each trainee will have academic otolaryngology faculty as either a primary or a secondary mentor. Emphasis will be placed on project design/translational potential, multidisciplinary collaboration, grantsmanship, manuscript development, and presentation of research proposals and findings. Opportunities will be provided to attend extramural or intramural conferences or educational courses relevant to the trainee's chosen research discipline. The research programs and facilities of the Department of Otolaryngology-Head and Neck Surgery and the Kresge Hearing Research Institute are among the best in the world and represent a major strength. The Michigan Institute for Clinical and Health Research (MICHR), funded by a Clinical Translational Science Award, sponsors outstanding training opportunities in clinical research as well as resources for clinical research. In addition, the University of Michigan has extensive investments in both clinical and basic research in terms of numerous core facilities, and major cross- departmental centers.