Ghana IntegRative Approach to Cancer ResEarch Training: The Grace Program

项目摘要/摘要 在许多撒哈拉以南非洲国家，癌症发病率正在显著增加，这需要改变 培训和研究，以解决这一日益严重的问题。几年前，加纳认识到了这个问题，并 在他们的国家癌症控制计划中，确定了研究和临床护理的优先癌症地点。 这些癌症包括乳腺癌(BCA)、子宫颈癌(CxCA)、头颈部癌(HNCA)和前列腺癌(PCA)。至 解决国家癌症计划中提出的目标莫菲特癌症中心(MCC)的教职员工已经 与加纳大学(UG)内的Korle-Bu教学医院和加纳学院合作 在过去的五年里，医生和外科医生(GCP)建立了合作研究和癌症临床 护理能力。这项工作最初侧重于PCa和HNCA，这是两种共同关注的癌症和 感兴趣，因为与这些癌症相关的发病率和死亡率不成比例地影响加纳人和 我们非洲裔美国人。认识到有必要将研究扩大到加纳的BCA和CxCa 合作准备将努力扩大到这两种额外的癌症，并扩大现有的研究和 培训协作，以创建具有更大深度和广度的全面、结构化的计划。我们 提议扩大加纳现有的合作机构名单，将加纳大学包括在内 医学院(UGMS)、公共卫生学院(UGSPH)和护理学院。此外，我们计划适应 作为完成的Fogarty D43摩洛哥的一部分开发的综合癌症研究培训计划 Grant，以加快在加纳实施癌症研究培训。这项提案的总体目标是 是在MCC和UG培养新一代多学科的全球健康癌症研究人员 实施将加强和扩大机构能力以广泛开展癌症的方案 研究-加纳癌症研究综合方法培训：GRACE计划。具体来说，我们 提出以下建议：1.建立和实施癌症研究培训和能力(讲座和讲习班 和应用研究经验)；2.基金团队-科学研究；3.转移和维持 加纳癌症研究培训计划。五年后，我们将培养出新一代的 研究员和初级教员(约125-150人)，并将可持续的 癌症研究培训计划，以支持加纳癌症研究的持续增长。拟议中的培训 该计划将促进从事肿瘤学的内科科学家的研究，并招募有才华的人 相关健康领域的专业人士进行癌症研究，从而迅速扩大癌症研究 在加纳。通过吸引来自多个学科的人员，拟议的计划将加强加纳现有的 国家和多学科癌症专项研究团队。最终，我们的目标是进行这种培训 该计划是学术界、政策制定者和公共卫生社区之间的桥梁。

Project Summary/Abstract Cancer incidence is significantly increasing in many sub-Saharan Africa countries necessitating a shift in training and research to address this growing problem. Years ago Ghana recognized this problem and identified cancer sites for prioritization for both research and clinical care in their National Cancer Control Plan. These cancers include breast (BCa), cervical (CxCa), head and neck (HNCa) and prostate cancer (PCa). To address the goals set forth in the national cancer plan Moffitt Cancer Center (MCC) faculty have been collaborating with the Korle-Bu Teaching Hospital within the University of Ghana (UG), and the Ghana College of Physician and Surgeons (GCPS) for the past five years to build collaborative research and cancer clinical care capacity. This work started initially with a focus on PCa and HNCa, two cancers of common concern and interest, as the incidence and mortality associated with these cancers disproportionally affects Ghanaians and US African Americans. Recognizing the need to expand research to BCa and CxCa in Ghana the MCC-Ghana collaboration is poised to expand efforts to these two additional cancers and to expand existing research and training collaborations to create a comprehensive and structured program with greater depth and breadth. We propose to expand the existing list of collaborating institutions in Ghana to include the University of Ghana Medical School (UGMS), School of Public Health (UGSPH), and Nursing School. In addition, we plan to adapt a comprehensive cancer research training program developed as part of a completed Fogarty D43 Morocco grant, to accelerate the implementation of cancer research training in Ghana. The overall goal of this proposal is to develop a new generation of multidisciplinary global health cancer researchers at MCC and UG by implementing programs that will strengthen and expand institutional capacity to broadly conduct cancer research - Ghana IntegRative Approach to Cancer ResEarch Training: The GRACE Program. Specifically, we propose the following: 1. Build and implement cancer research training and capacity (Lectures and Workshops and an Applied Research Experience); 2. Fund Team-Science Research, and; 3. Transfer and sustain the Ghana cancer research training program. At the end of five years we will have trained a new generation of fellows and junior faculty (~125-150) and embedded into the Ghana medical education system a sustainable cancer research training program to support continued cancer research growth in Ghana. The proposed training program will advance research among physician scientists practicing oncology and recruit talented professionals from related health fields to conduct cancer research, thereby rapidly expanding cancer research in Ghana. By engaging those from multiple disciplines, the proposed program will strengthen Ghana’s existing national and multidisciplinary cancer-specific research teams. Ultimately, our goal is to have this training program serve as a bridge between academic, policy makers, and public health communities.