Clinical, Laboratory, and Data Management Core

摘要 临床、实验室和数据管理核心（核心B）提供了确保一致性 为CRISP 2中提出的实验室研究采集临床数据、样本和样本衍生物。 此外，由于核心B（1-6）具有丰富的经验和专业知识，因此它将用于验证和 如有需要，传播新的样本采集、处理或分析规程。核心B还服务于 作为炎症细胞因子内型分析的基础，为提案中的所有项目服务。实现这些 核心B包括三个主要组成部分-临床、实验室和数据管理， 提供基础设施、培训和专门知识。虽然自2004年以来一直作为事实上的中心运作，但核心 2012年正式成立，以支持CRISP 1。这些服务将予以维持，以便为下列人员提供最佳支助： CRISP 2，必要时升级，继续提供全面和综合的临床，实验室和 数据管理功能

ABSTRACT The Clinical, Laboratory and Data Management Core (Core B) provides the infrastructure for ensuring consistent acquisition of clinical data, samples and sample derivatives for the laboratory studies proposed in CRISP2. Additionally, because significant experience and expertise resides in Core B(1-6), it will serve to validate and disseminate new protocols for sample acquisition, processing or analysis should needs arise. Core B also serves as the base for inflammatory cytokine endotyping assays that serve all projects in the proposal. To achieve these goals, Core B encompasses three major components – clinical, laboratory and data management– that will provide infrastructure, training and expertise. Although functioning as a de facto center since 2004, the core was formally established in 2012 to support CRISP1. These services will be maintained to provide optimal support to CRISP2, upgrading as necessary to continue providing comprehensive and integrated clinical, laboratory and data management.