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Enhancing Partner Services among Men Who Have Sex with Men Living With HIV: A Pilot Randomized Controlled Trial

Enhancing Partner Services among Men Who Have Sex with Men Living With HIV: A Pilot Randomized Controlled Trial
加强男男性行为艾滋病毒感染者的伴侣服务:一项试点随机对照试验
批准号:
10227179
负责人:
Weiming Tang
金额:
$18.67万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-08-08 至 2024-03-31

项目摘要

项目成果

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中文摘要
翻译
项目标题:加强与艾滋病毒携带者发生性行为的男性的合作伙伴服务 试验性随机对照试验 尽管全球努力控制关键人群中的艾滋病毒,但与之发生性关系的男性中出现了新的感染 男性(MSM)仍在增加。为了应对这一挑战,高效的艾滋病毒预防战略是 急需之物。伙伴服务(PS),告知潜在的性接触风险的过程 合作伙伴,是预防艾滋病毒的基石。PS对于识别病例、减少再次感染很重要 费率,促进与护理挂钩,并降低成本。然而,来自医疗服务提供者和 首发病例限制了PS的疗效。因此,PS在许多国家都没有得到充分利用,包括中国 只有16%的艾滋病患者配偶得到了通知。众包可以用来改善 PS的有效性。众包是一种从社区获得解决方案的方法。 众包已被有效地用于公共卫生,以改进艾滋病毒检测,促进避孕套的使用,以及 监测疫情。作为一种自下而上的方法,众包可以有效地吸引MSM和其他 利益相关者发表意见,以增进对艾滋病毒PS的了解,并设计以参与者为导向的 干预措施。与MSM相比,为PS开发的众包消息可能会引起更强烈的共鸣 到传统的PS消息。反过来,这可能会导致更多的社区参与和接受 HIV PS,提高HIV PS的有效性。我们假设众包HIV PS的方法是 这是可行的,可以接受的。我们还假设,与使用推荐卡的传统PS相比 (中国的护理标准),将产生:a)更多的性伴侣报告艾滋病毒检测,以及b)更多的性行为 已确认感染艾滋病毒的伴侣。我们的多学科研究团队将众包和PS结合在一起 经验,中国与MSM合作的历史,以及当地丰富的艾滋病毒研究基础设施,以 研究目标如下:(1)利用OPEN为中国MSM开发众包式PS干预 竞争;(2)测试众包PS的可行性、可接受性和试点初步影响 在新发现的MSM病例的合作伙伴中促进艾滋病毒检测的常规PS 先导随机对照试验。在这个试点项目中,我们将首先使用公开竞赛来开发一个 对中国MSM进行众包PS干预,然后我们将进行一项试点RCT,其中索引MSM 患者随机接受众包干预或标准护理,比例为2:1。 将制定众包干预战略,促进艾滋病毒个人健康,并收集初步数据,以便 全面随机对照试验,旨在进一步评估众包PS在多个 中国的城市。 ?
英文摘要
Project title: Enhancing Partner Services among Men Who Have Sex with Men Living With HIV: A Pilot Randomized Controlled Trial Despite global efforts to control HIV among key populations, new infections among men who have sex with men (MSM) are still increasing. To deal with this challenge, HIV prevention strategies with high efficacy are urgently needed. Partner services (PS), the process of informing potential risk of exposure to sexual partners, is a cornerstone of HIV prevention. PS are important for identifying cases, reducing re-infection rates, promoting linkage to care, and reducing costs. However, barriers from both health providers and index cases limit the efficacy of PS. As a result, PS is underused in many countries, including China where only 16% of index HIV case spouses were notified. Crowdsourcing can be used to improve the effectiveness of PS. Crowdsourcing is an approach that obtains solutions from communities. Crowdsourcing has been used effectively in public health to improve HIV testing, promote condom use, and monitor outbreaks. As a bottom-up approach, crowdsourcing can effectively engage MSM and other stakeholders to contribute their voices to enhance understanding of HIV PS and design participant-oriented interventions. Crowdsourced messages developed for PS may resonate more strongly with MSM compared to traditional PS messages. In turn, this could lead to increased community participation and acceptance of HIV PS, improving the effectiveness of HIV PS. We hypothesize that a crowdsourced HIV PS approach is feasible and acceptable. We also hypothesize that, as compared to conventional PS using referral cards (standard of care in China), will yield: a) more sexual partners reporting for HIV testing, and b) more sexual partners with confirmed HIV. Our multi-disciplinary research team brings together crowdsourcing and PS experience, a history of working with MSM in China, and a rich local infrastructure for HIV research, to investigate the following aims: (1) to develop a crowdsourced PS intervention for Chinese MSM using open contests; (2) to test the feasibility, acceptability and pilot the preliminary impact of crowdsourced PS with conventional PS on promoting HIV testing uptake among partners of newly identified MSM cases using a pilot randomized controlled trial. In this pilot project, we will first use open contests to develop a crowdsourced PS intervention for Chinese MSM, then we will conduct a pilot RCT in which index MSM cases are randomized to receive crowdsourced intervention or standard of care in a ratio of 2:1. The project will develop crowdsourced intervention strategies for promoting HIV PS, and collect preliminary data for a full RCT that aims to further evaluate the efficacy and cost-effectiveness of crowdsourced PS in multiple Chinese cities. ?
期刊论文(32)
专著(0)
科研奖励(0)
会议论文
A Tempo-geographic Analysis of Global COVID-19 Epidemic Outside of China.
中国以外全球 COVID-19 疫情的时空地理分析。
DOI: 10.1101/2020.03.20.20039602
发表时间: 2020
期刊: medRxiv : the preprint server for health sciences
影响因子: --
作者: [Liao,Huipeng, Marley,Gifty, Si,Yafei, Wang,Zaisheng, Xie,Yewei, Wang,Cheng, Tang,Weiming]
通讯作者: Tang,Weiming
DOI: 10.1007/s12529-023-10177-y
发表时间: 2024-04
期刊: International journal of behavioral medicine
影响因子: 2.7
作者: []
通讯作者:
Humoral Immune Response to Inactivated COVID-19 Vaccination at the 3rd Month among People Living with HIV.
HIV 感染者在第 3 个月对灭活 COVID-19 疫苗接种的体液免疫反应。
DOI: 10.21203/rs.3.rs-1750225/v1
发表时间: 2022
期刊: Research square
影响因子: --
作者: [Wu,Songjie, Zou,Shi, Ming,Fangzhao, Wu,Mengmeng, Guo,Wei, Xing,Zhongyuan, Zhang,Zhiyue, Liu,Jinli, Tang,Weiming, Liang,Ke]
通讯作者: Liang,Ke
DOI: 10.1186/s12981-022-00459-y
发表时间: 2022-07-05
期刊: AIDS research and therapy
影响因子: 2.2
作者: []
通讯作者:
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