Scientific Core
Scientific Core
批准号:
10343674
负责人:
Maria Acena Nagel
金额:
$28.61万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-03-01 至 2023-12-31
关键词:
BioinformaticsClinicalClinical DataColoradoComputersContract ServicesDataData AnalysesDiseaseElderlyEnsureEquipmentEquipment and SuppliesFoundationsFundingGene Expression ProfilingGoalsGrantHerpesvirus Type 3HumanHuman ResourcesInflammationInstitutional Review BoardsInvestigationLaboratory PersonnelMaintenanceMonkeysProcessPublicationsSpecimenTissuesVisioncomputerizedcosteditorialhuman tissuelaboratory experienceorganizational structureprogramsrepairedtissue culturetranscriptome sequencing
中文摘要
科学核心为科学工作提供了一个组织结构,
计划,以实现总体目标和愿景的计划项目作为一个综合的调查,
VZV引起的老年人疾病。核心负责人Maria内格尔博士会见临床协调员
每天对所有人类和猴子标本的科学工作进行优先排序,并计划战略和评估
数据科学核心为临床协调员提供支持,临床协调员将获取、储存、处理和
在项目1和项目2中计算来自人类的所有组织,在项目3中计算来自猴子的所有组织,以及确保
遵守监管机构,包括科罗拉多多机构审查委员会。科学
Core还为所有3个项目提供支持:生物信息学专家协助RNA测序,数据
分析和解释,以及在这些分析中培训实验室人员;统计顾问;
编辑顾问和出版费用;组织培养、PCR和
基因表达谱分析/RNA测序;以及继续服务合同,
设备和计算机费用。
英文摘要
The Scientific Core provides an organizational structure for scientific efforts common to all projects within the
program to achieve the overall goals and vision of the Program Project as an integrated investigation in
diseases caused by VZV in the elderly. The Core Leader, Dr. Maria Nagel, meets with the Clinical Coordinator
daily to prioritize scientific efforts on all human and monkey specimens and to plan strategies and evaluate
data. The Scientific Core provides support for the Clinical Coordinator, who will acquire, bank, process and
computerize all tissue from humans in Projects 1 and 2 and from monkeys in Project 3, as well as ensure
compliance with regulatory bodies including the Colorado Multiple Institutional Review Board. The Scientific
Core also provides support in all 3 projects for: a bioinformatics expert to assist with RNA sequencing, data
analysis and interpretation, and training of laboratory personnel in these analyses; a statistical consultant; an
editorial consultant and publication costs; common-use supplies and equipment for tissue culture, PCR and
gene expression profiling/RNA sequencing; and continuing service contracts, maintenance and repair of heavy
equipment and computer costs.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Virus and olfactory system interactions accelerate Alzheimer's disease pathology
-
批准号:10669880
-
项目类别:
-
资助金额:$103.75万
-
财政年份:2023
-
负责人:Maria Acena Nagel
-
依托单位:
Purinergic Signaling in Varicella Zoster Virus Vasculopathy
-
批准号:9331756
-
项目类别:
-
资助金额:$34.02万
-
财政年份:2015
-
负责人:Maria Acena Nagel
-
依托单位:
Purinergic Signaling in Varicella Zoster Virus Vasculopathy
-
批准号:9128742
-
项目类别:
-
资助金额:$34.02万
-
财政年份:2015
-
负责人:Maria Acena Nagel
-
依托单位:
Administrative Core
-
批准号:10542741
-
项目类别:
-
资助金额:$10.9万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Scientific Core
-
批准号:10542742
-
项目类别:
-
资助金额:$26.16万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
A major contributor of serious multisystem disease in the elderly: varicella zoster virus-induced inflammation
-
批准号:10542740
-
项目类别:
-
资助金额:$219.91万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
A major contributor of serious multisystem disease in the elderly: varicella zoster virus-induced inflammation
-
批准号:9491544
-
项目类别:
-
资助金额:$236.43万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
The Molecular Pathogenesis of Varicella Zoster Virus Infection
-
批准号:9027774
-
项目类别:
-
资助金额:$185.84万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
The Molecular Pathogenesis of Varicella Zoster Virus Infection
-
批准号:9306675
-
项目类别:
-
资助金额:$7.75万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
A major contributor of serious multisystem disease in the elderly: varicella zoster virus-induced inflammation
-
批准号:10097948
-
项目类别:
-
资助金额:$233.98万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Administrative Core
-
批准号:9491545
-
项目类别:
-
资助金额:$11.66万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Scientific Core
-
批准号:10097961
-
项目类别:
-
资助金额:$30.97万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Mechanisms by which VZV IE proteins interact with cell antiviral proteins to prev
-
批准号:8320861
-
项目类别:
-
资助金额:$18.74万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Mechanisms by which VZV IE proteins interact with cell antiviral proteins to prev
-
批准号:8513423
-
项目类别:
-
资助金额:$18.74万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
The Molecular Pathogenesis of Varicella Zoster Virus Infection
-
批准号:9781521
-
项目类别:
-
资助金额:$34.55万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Characterizing the VZV-induced inflammatory response in temporal arteries from patients with giant cell arteritis
-
批准号:10343675
-
项目类别:
-
资助金额:$42.68万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
The role of VZV infection in hippocampal neurons to Alzheimer's disease pathogenesis
-
批准号:10289595
-
项目类别:
-
资助金额:$37.46万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Scientific Core
-
批准号:9491546
-
项目类别:
-
资助金额:$31.95万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Characterizing the VZV-induced inflammatory response in temporal arteries from patients with giant cell arteritis
-
批准号:9491547
-
项目类别:
-
资助金额:$44.95万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
Administrative Core
-
批准号:10343673
-
项目类别:
-
资助金额:$14.44万
-
财政年份:2009
-
负责人:Maria Acena Nagel
-
依托单位:
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
-
批准号:31070748
-
项目类别:面上项目
-
资助金额:34.0万元
-
批准年份:2010
-
负责人:Christine Nardini
-
依托单位: