RESEARCH IN DEVELOPMENTAL ENDOCRINOLOGY AND METABOLISM

波士顿儿童医院（BCH）的发育内分泌学和代谢培训补助金 计划每年资助4名博士后研究员从事研究培训， 在学术儿科内分泌学的独立职业。该计划旨在解决 学术儿科专家，包括儿科内分泌学家，并培养未来的内科医生 将利用研究解决肥胖和糖尿病等紧迫问题的领导人。学员（4人） 每年的名额）主要是从6至9名高素质的儿科内分泌学博士后中挑选出来的 研究员谁是在BCH内分泌学奖学金计划的部门或不到一年后 方案的完成。计划的平均培训时间为两年。学员进入项目 拥有医学博士（或同等学历）、医学博士/博士学位或偶尔拥有博士学位。 32名培训人员包括13名临床活跃的儿科内分泌医生-科学家，10名儿科医生-科学家， 其他学科，11名MD/PhD和6名博士科学家。BCH是主要的培训地点，但研究员也在 马萨诸塞州总医院，贝斯以色列女执事医疗中心，布里格姆妇女医院， 乔斯林糖尿病中心和怀特黑德研究所。本次培训重点研究的主要领域 资助项目包括糖尿病及其并发症的临床、转化和基础实验室研究， 肥胖及其并发症，饮食/代谢和健康，神经内分泌学，骨骼健康和生物学， 肠道生物学和发育内分泌学，性别差异和内分泌疾病，内分泌 癌的培训由教学课程组成，包括定量方法、研究的道德行为， 和可重复性/严谨性，以及一个单独指导研究的密集期。在34名受训人员中， 在过去的15年里，谁已经完成了这个T32补助金的培训，30是学术儿科或 研究机构，两个在工业界，一个在FDA。在这30人中，有13名助理 教授、副教授5名、教授1名、处长2名、项目主任10名。的纪录 出版是强大的，因为是他们的赠款资金记录：12个独立的NIH K奖，4个有 R 03或R21奖励，5个有一个或多个R 01。该计划利用科学的广度 内分泌科以及更大的BCH社区内培训教师的专业知识 和周围哈佛的环境。我们为学员提供严格和刺激的培训 环境，有许多优秀的课程，尖端的研讨会，和杰出的导师谁部署的 最新的研究方法。凭借高素质的学员和过去成功的记录，我们希望继续 培养下一代多元化的学术儿科内分泌学家和医学科学家领导者。

This training grant in developmental endocrinology and metabolism at Boston Children's Hospital (BCH) intends to provide funding for 4 postdoctoral fellows per year to engage in research training leading to independent careers in academic pediatric endocrinology. The program is designed to address the shortage in academic pediatric subspecialists, including pediatric endocrinologists, and train future physician-sicentist leaders who will use research to address pressing problems such as obesity and diabetes. The trainees (4 slots per year) are largely selected from a pool of 6 to 9 highly qualified pediatric endocrinology postdoctoral fellows who are in the BCH Division of Endocrinology Fellowship Program or less than one year after completion of the program. The intended average duration of training is two years. Trainees enter the program with either the MD (or equivalent), MD/PhD or occasionally the PhD degree. The 32 trainers include 13 clinically active pediatric endocrine physician-scientists, 10 physician-scientists of other disciplines, 11 MD/PhDs, and 6 PhD scientists. BCH is the major training site, but fellows also train at Massachusetts General Hospital, Beth Israel Deaconess Medical Center, Brigham and Women’s Hospital, Joslin Diabetes Center, and the Whitehead Institute. The major areas of research emphasis in this training grant include clinical, translational and basic laboratory research in diabetes mellitus and its complications, obesity and its complications, diet/metabolism and health, neuroendocrinology, skeletal health and biology, intestinal biology and developmental endocrinology, sex differences and endocrine disease, and endocrine cancers. Training consists of didactic courses, including in quantitative methods, ethical conduct of research, and reproducibility/rigor, and an intensive period of individually mentored research. Of the 34 trainees during the past 15 years who have completed training on this T32 grant, 30 are faculty in academic pediatric or research institutions, two are in industry, and one is at the FDA. Of these 30, there are 13 Assistant Professors, 5 Associate Professors, 1 Professor, 2 Division Chiefs, and 10 Program Directors. Their record of publication is strong, as is their record of grant funding: 12 have had independent NIH K awards, 4 have had R03 or R21 awards, and 5 have one or more R01s. This program takes advantage of the breadth of scientific expertise of the training faculty within the Division of Endocrinology, as well as in the larger BCH community and surrounding Harvard environment. We provide trainees with a rigorous and stimulating training environment, with many excellent courses, cutting-edge seminars, and outstanding mentors who deploy the latest research methods. With highly qualified trainees and a track record of past success, we hope to continue to train a next generation of diverse academic pediatric endocrinologists and physician-scientist leaders.