Exposure Science Facility

项目总结-暴露科学工厂（ESF） 暴露科学设施（ESF）的主要目标是促进EHSRC的研究工作 研究人员试图了解对结果产生不利影响的外部环境压力 暴露之后。ESF通过以下具体目标来实现这一目标： 用于空气污染物建模和暴露评估的资源和专业知识;目标2）支持 EHSRC主题领域、试点研究、CEC活动和指导准会员;目标3）促进 EHSRC研究人员之间的多学科研究;目的4）提供专业知识，以及促进 在接触评估和基于健康的调查的连续过程中， 博士前，博士后和准会员培训建模和暴露评估方法。 ESF由一组在其广泛领域具有长期专业知识的调查人员提供支持， 目标，包括环境污染物采样、工业卫生实践、健康物理学、空气 分散建模，计算流体动力学建模，以及与所有相关的化学分析方法 暴露的途径。ESF在EHSRC中发挥关键作用，协助各级调查人员， 试点赠款接受者，以适当地确定，量化和模拟环境污染物，并量化风险。 ESF致力于开发和维护仪器和建模能力，这有助于研究人员 将环境污染物与健康结果联系起来。因此，ESF对以下方面至关重要： EHSRC的研究人员试图了解人类健康与疾病之间的复杂联系， 麻烦ESF通过收集最先进的仪器和实验室来实现其目标。 结合起来，它们包括各种各样的仪器，用于采样气体，蒸汽和气溶胶，此外， 到那些能够分析复杂基质中的各种化合物，包括水，食物，空气， 血液和组织样本ESF建模功能包括用于确定空间分布的功能 空气污染物和人体肺部颗粒物的沉积。ESF领导层和教职员工提供 咨询和培训EHSRC研究人员规划研究项目，包括评估 环境暴露对人体健康的影响。ESF是爱荷华州大学校园内的一个独特设施， 与其中心设施有着密切的联系。连同这些设施和其收藏的仪器 和相关支持，ESF允许EHSRC调查人员在征求时准备成本效益预算 为他们的研究提供校外资金。

PROJECT SUMMARY - EXPOSURE SCIENCE FACILITY (ESF) The primary goal of the Exposure Science Facility (ESF) is to facilitate the research efforts of EHSRC investigators as they seek to understand the external environmental stressors that adversely affect outcomes following an exposure. The ESF addresses this goal through the following specific aims: Aim 1) Provide resources and expertise for modeling of airborne contaminants and exposure assessment; Aim 2) support EHSRC Thematic Areas, pilot studies, CEC activities, and mentored Associate Members; Aim 3) facilitate multidisciplinary research among EHSRC investigators; Aim 4) provide expertise, as well as facilitate interaction, in the continuum of exposure assessment and health-based investigation; and Aim 5) facilitate pre-doctoral, post-doctoral and Associate Member training in modeling and exposure assessment methods. The ESF is supported by a team of investigators with longstanding expertise in the wide-ranging aspects of its Aims, including expertise in environmental pollutant sampling, industrial hygiene practices, health physics, air dispersion modeling, computational fluid dynamics modeling, and chemical analytical methods related to all routes of exposure. The ESF provides a critical role within the EHSRC by aiding investigators at all levels and pilot grant recipients to properly identify, quantify and model environmental contaminants, and quantify risk. The ESF strives to develop and maintain instrumentation and modeling capabilities, which help investigators link environmental contaminants with health outcomes. The ESF is therefore of fundamental importance to EHSRC investigators as they seek to understand the complicated linkages between human health and the exposome. The ESF achieves its goals through its collection of state-of-the-art instruments and laboratories. Combined, they include a wide variety of instruments used to sample gases, vapors, and aerosols in addition to those capable of analyzing various chemical compounds in complex matrices, including water, food, air, blood, and tissue samples. ESF modeling capabilities include those used to determine the spatial distribution of air pollutants and the deposition of particles in the human lung. ESF leadership faculty and staff provide consultation and training to EHSRC investigators planning research projects involving the assessment of environmental exposures on human health. The ESF is a unique facility on the University of Iowa campus that has strong associations with its central facilities. Together with these facilities and its collection of instruments and related support, the ESF allows EHSRC investigators to prepare cost-effective budgets when soliciting extramural funds for their research.