Southern California Center for Children’s Environmental Health Translational Research

总体：项目摘要/摘要 近道路和区域空气污染、工业排放、货物流动和不断增长的石油和天然气 易受野火影响的城市地区的生产都有可能增加环境疾病的负担。在……里面 在加利福尼亚州和全世界，这些威胁对儿童的影响不成比例，特别是在边缘化社区 和有色人种的社区。空气污染对儿童呼吸健康、肥胖和新陈代谢有不利影响 结果和神经发育。需要新的儿童环境健康科学(CEHS)翻译 制定和实施有效的、以科学为基础的干预措施，以应对这些不利趋势。这个 南加州儿童环境健康转化研究中心的使命 CCEHTR)是利用科学知识通过以下方式减少与环境有关的疾病的负担 发展：(1)多学科CEHS翻译团队构建多方向、 面向行动的与社区、学术界和政策制定者的接触，以及(2)模式协作 支持初级调查人员和社区使用新兴的CEHS，导致更好的决策。 因此，SC-CCEHTR的主题是城市主义、空气污染、儿童健康和环境 正义。SC-CCEHTR将建立在CEHS跨越三个NIEHS中心的大型赠款基础上 以及与社区和决策者进行创新的多方向接触。拟议的资深大律师委员会- CCEHTR框架包括青年参与和社区科学、城市设计的新方法 和政策解决方案，以及沟通和公共知识。来自通讯的CEHS新手调查人员， 政策和城市设计、社会学、戏剧艺术、教育、网络分析和实施科学将 将新的方法引入这一框架，专注于通过“重新想象”来确定城市空气污染的解决方案 该城市的设计旨在减少空气污染暴露，改善儿童健康。翻译核心将带来 SC-CCEHTR工具将用于开发试点项目，以更好地将CEHS转化为社区 知识和行动。发展核心回应初级调查员的职业发展需求和 应对新出现的CEHS挑战。将促进创新的翻译和职业发展合作 随着环境正义社区网络的发展，国际儿童协会 健康与环境，其他儿童环境健康研究翻译中心和NIEHS P30核心中心和全国各地的政策制定者。

OVERALL: PROJECT SUMMARY/ABSTRACT Near-roadway and regional air pollution, industrial releases, goods movement and growing oil and gas production in urban areas vulnerable to wildfires all threaten to increase the burden of environmental disease. In California and worldwide, these threats disproportionately affect children, especially in marginalized communities and communities of color. Air pollution has adverse effects on childhood respiratory health, obesity and metabolic outcomes, and neurodevelopment. New children’s environmental health science (CEHS) translation is needed to develop and implement effective, science-based interventions to address these unfavorable trends. The mission of the Southern California Center for Children’s Environmental Health Translational Research (SC- CCEHTR) is to leverage scientific knowledge to reduce the burden of environmentally related diseases by developing: (1) multidisciplinary CEHS translational teams building an innovative framework for multidirectional, action-oriented engagement with communities, academia and policymakers, and (2) model collaborations supporting junior investigators and communities to use emerging CEHS, leading to better decision-making. Accordingly, the theme of the SC-CCEHTR is Urbanism, Air Pollution, Children’s Health and Environmental Justice. The SC-CCEHTR will build on a foundation of a large CEHS grant base across three NIEHS Centers and of innovative multidirectional engagement with communities and decision-makers. The proposed SC- CCEHTR framework includes novel approaches to youth engagement and community science, urban design and policy solutions, and communication and public knowledge. Investigators new to CEHS from communication, policy and urban design, sociology, dramatic arts, education, network analysis and implementation science will bring fresh approaches to this framework, focused on identifying solutions to urban air pollution by “re-imagining” the design of the city to reduce air pollution exposure and improve children’s health. A Translation Core will bring the SC-CCEHTR tools to bear on the development of pilot projects to better translate CEHS into community knowledge and action. A Developmental Core responds to career development needs of junior investigators and to emerging CEHS challenges. Innovative translational and career development collaborations will be promoted with the Moving Forward Network of environmental justice communities, the International Society for Children’s Health and the Environment, other Children's Environmental Health Research Translation Centers and NIEHS P30 Core Centers, and policymakers across the country.